Efeito do alopurinol sobre a morfologia do testículo do rato submetido a isquemia, pela torção do cordão espermático seguida de reperfusão
PURPOSE: In this investigation has been studied the effect of the alopurinol on the reperfusion injury phenomenon in testicles of rats. METHODS: Eighty adults Wistar rats were divided in 4 groups: sham without alopurinol, sham with alopurinol, rigth testicular torsion for one hour without alopurinol...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2005 |
| País: | Brasil |
| Institución: | Universidade Federal de São Paulo (UNIFESP) |
| Repositorio: | Repositório Institucional da UNIFESP |
| Idioma: | portugués |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/2827 |
| Acceso en línea: | http://dx.doi.org/10.1590/S0102-86502005000600013 http://repositorio.unifesp.br/handle/11600/2827 |
| Access Level: | acceso abierto |
| Palabra clave: | Spermatic Cord Torsion Testis Allopurinol Rats Torsão do Cordão Espermático Testículo Alopurinol Ratos |
| Sumario: | PURPOSE: In this investigation has been studied the effect of the alopurinol on the reperfusion injury phenomenon in testicles of rats. METHODS: Eighty adults Wistar rats were divided in 4 groups: sham without alopurinol, sham with alopurinol, rigth testicular torsion for one hour without alopurinol and rigth testicular torsion for one hour with alopurinol. Bilateral orchiectomy was performed 60 days of the experiment and the testis were precessed for optical microscopy, and edamined to asses the seminiferous ducts and the spermatogenic cells. RESULTS: There was significant atrophy and histological damage of the rigth testis. CONCLUSION: Alopurinol did not protected the testis against the effects of the reperfusion injury. |
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