Neutrophil-lymphocyte ratio in catatonia

There is growing evidence of subclinical inflammation in mental disorders. Objective: The aim of this study was to investigate frequency of symptoms of catatonia and the newly diagnosed subclinical inflammatory markers which are neutrophil/lymphocyte (NLR), platelet/lymphocyte (PLR), monocyte/lympho...

Descripción completa

Detalles Bibliográficos
Autores: Sahin, Sengul Kocamer, Yaşamali, Celal, Özyürek, Muhammet Berkay, Elboğa, Gülçin, Altindağ, Abdurrahman, Şahin, Ahmet Ziya
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Brasil
Institución:Universidade de São Paulo (USP)
Repositorio:Archives of Clinical Psychiatry
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/180674
Acceso en línea:https://revistas.usp.br/acp/article/view/180674
Access Level:acceso abierto
Palabra clave:Catatonia
inflammation
neutrophil-lymphocyte ratio
platelet lymphocyte ratio
monocyte/lymphocyte ratio
symptom frequency
Descripción
Sumario:There is growing evidence of subclinical inflammation in mental disorders. Objective: The aim of this study was to investigate frequency of symptoms of catatonia and the newly diagnosed subclinical inflammatory markers which are neutrophil/lymphocyte (NLR), platelet/lymphocyte (PLR), monocyte/lymphocyte (MLR) ratios in catatonia patients due to mental disorders. Methods: Patients who were admitted to psychiatry clinic with the diagnosis of catatonia according to DSM 5 in the last two years and equal number of control group were included in this retrospective study. Univariate analysis of covariance controlled for possible confounders was used to compare NLR, PLR, MLR ratios between patients and the control group. Results: A total of 34 catatonia patients and 34 healthy controls were included in the study. Patients’ mean age was 30.88 + 13.4. NLR value was significantly higher in the patient group than control group. There was no significant difference between the patients and control group according to PLR, MLR values. Discussion: The presence of subclinical inflammation in catatonic syndrome due to mental disorders should be considered. Subclinical inflammation that was observed in numerous mental disorders continues in catatonia due to mental disorders. Large-scale studies are needed to determine the role of inflammation in catatonia.