Potential health effects of tomato (lycopersicon esculentum) juice and hypoglycemic amelioration in the atherogenic indices between diabetic animal models
Abstract This study aimed firstly to evaluate the antioxidants levels (Lycopene & Beta-carotene) within fresh tomato juice (FTJ) and its health effects on atherogenic indices in association to lipid profiles and kidney functions between diabetic animal models. Rats (thirty-two; 180 ± 5 g) were r...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | Brasil |
| Institución: | Sociedade Brasileira de Ciência e Tecnologia de Alimentos (SBCTA) |
| Repositorio: | Food Science and Technology (Campinas) |
| Idioma: | inglés |
| OAI Identifier: | oai:scielo:S0101-20612022000101366 |
| Acceso en línea: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612022000101366 |
| Access Level: | acceso abierto |
| Palabra clave: | lycopene lipid profile streptozotocin glutathione peroxidase superoxide dismutase |
| Sumario: | Abstract This study aimed firstly to evaluate the antioxidants levels (Lycopene & Beta-carotene) within fresh tomato juice (FTJ) and its health effects on atherogenic indices in association to lipid profiles and kidney functions between diabetic animal models. Rats (thirty-two; 180 ± 5 g) were randomly divided to groups; control negative (G1; non-diabetic), control positive (G2; fed standard basil diet), and three diabetic groups induced by single dose of streptozotocin (STZ; 65 mg/kg body weight). Groups of diabetic G3 & G4 (given FTJ by gavages at 2 and 4 mL/day respectively). Glucose, lipid profile (Cholesterol, Triglyceride, LDL.c, HDL.c and VLDL.c), kidney functions with atherogenic indices; the activity of glutathione peroxidase (GSH.Px), glutathione reduced (GSH.Rd) and superoxide dismutase (SOD) were evaluated. Results expressed data indicated that fresh tomato juice antioxidant activities presented at 72.83 ± 2.62 while Lycopene and β-carotene levels were 10.37 ± 1.36 and 3.91 ± 0.22 mg/100 mL respectively. Also, FTJ administration at 4 mL/day was the best effective dose; glucose, cholesterol, triglyceride and LDL.c. However, an elevation in the HDL.c, GSH.Px, GSH.Rd, and SOD were seen compared to G2. In conclusion, fresh tomato juice had hypoglycemic and positive atherogenic indices/effects that enhanced the model lipid profile to nearly the normal levels between diabetic rats especially at 4 mL/day. |
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