Music therapy reduces fatigue of the patients undergoing autologous hematopoietic stem cells transplantation

Introduction: Autologous hematopoietic stem cell transplantation (HSCT) is a therapeutic medical treatment for various neoplastic hematologic, congenital, genetic, or acquired disorders. In this procedure which combines high-dose chemotherapy and/or radiotherapy and has a high degree of cytotoxicity...

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Detalhes bibliográficos
Autores: Dóro, Carlos Antonio, Zulato, Adriana Gonçalves, Azevedo, Valderilio Feijó
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:Brasil
Recursos:Faculdade de Medicina do ABC (FMABC)
Repositorio:ABCS Health Sciences (Online)
Idioma:inglés
OAI Identifier:oai:ojs.emnuvens.com.br:article/2867
Acesso em linha:https://www.portalnepas.org.br/abcshs/article/view/2867
Access Level:acceso abierto
Palavra-chave:music therapy
fatigue
hematopoietic stem cell transplantation
transplantation, autologous
Descrição
Resumo:Introduction: Autologous hematopoietic stem cell transplantation (HSCT) is a therapeutic medical treatment for various neoplastic hematologic, congenital, genetic, or acquired disorders. In this procedure which combines high-dose chemotherapy and/or radiotherapy and has a high degree of cytotoxicity, the patient experiences solitary confinement, which causes psychological distress, anxiety, mood disorder, fatigue, nausea, and pain and can lead him/her to depression. Objective: Evaluate the effectiveness of music therapy intervention for fatigue in patients undergoing autologous hematopoietic stem cell transplantation. Methods: This is a randomized clinical trial patients (n=151) were selected randomly were selected for the Experimental Music Therapy Group (EMG, n=76) which received the intervention, and for the Control Group (CG, n=75) which received only standard treatment. Interventions of live music were made using music therapy methods and techniques by a qualified music therapist. For assessment and quantification, the visual analog scale (VAS), and piper fatigue scale (PFS) were used. Results: The analysis and statistical tests applied were considered statistically significant. (PFS) Score Total (EMG) Baseline 7.1 (CG) 6.7 p=0.30 follow up (EMG) 2.4 (CG) 5.7=2.4 p<0.001 (VAS) before intervention 6.45 p=0.89 after intervention 2.52 p<0.001. Conclusion: Music therapy reduces fatigue of the undergoing autologous hematopoietic stem cell transplantation, providing bio-psychosocial welfare.