Quality of the package inserts of phytomedicines in Brazil

The objective of this study was to assess whether the package inserts of industrialized phytomedicines are in line with current Brazilian legislation or not. Forty-one package inserts of phytomedicines containing artichoke, horse chestnut, ginkgo and senna were accessed in the respective proprietary...

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Detalles Bibliográficos
Autores: da Silva, Jéssica Domingos, Passos, Márcia Maria Barros dos, Simas, Naomi Kato, dos Santos, Maria Isabel Sampaio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Vigilância Sanitária em Debate
Idioma:portugués
OAI Identifier:oai:ojs.visaemdebate.incqs.fiocruz.br:article/677
Acceso en línea:https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/677
Access Level:acceso abierto
Palabra clave:Bulas de Medicamentos
Fitoterápicos
Legislação Sanitária
Vigilância Sanitária
Medicine Package Inserts
Phytomedicines
Health Legislation
Health Surveillance
Descripción
Sumario:The objective of this study was to assess whether the package inserts of industrialized phytomedicines are in line with current Brazilian legislation or not. Forty-one package inserts of phytomedicines containing artichoke, horse chestnut, ginkgo and senna were accessed in the respective proprietary websites and then analyzed. The analysis aimed to verify the presence of items required by the normative RDC 47/2009 and the usage indication, dosage and side effects compared to standard package inserts and to the scientific literature. Quantitative analysis proved that the package inserts are in accordance with the current legislation. However, in qualitative analysis, all phytomedicines analyzed in this study had at least one error related to dosage, posology or adverse reactions. A gradual improvement of the package inserts of phytomedicines has been noticed but, even with the availability of standard package inserts, some mistakes persist, which can induce the patient to incorrect use.