Prevalence of pancreatic autoantibodies in non-diabetic patients with autoimmune thyroid disease and its relation to insulin secretion and glucose tolerance

Objective: We evaluated the prevalence of glutamic acid decarboxylase (GADA) and tyrosine phosphatase-protein antibodies (IA2A), their titers and their relation to first phase insulin response (FPIR) and glucose tolerance in autoimmune thyroid diseases (ATDs) patients. Subjects and methods: Graves&#...

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Detalles Bibliográficos
Autores: Sallorenzo, Carolina [UNIFESP], Silva, Regina [UNIFESP], Kasamatsu, Teresa [UNIFESP], Dib, Sergio [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/53496
Acceso en línea:http://dx.doi.org/10.1590/2359-3997000000280
https://repositorio.unifesp.br/handle/11600/53496
Access Level:acceso abierto
Palabra clave:Autoimmune thyroid disease
pancreatic autoantibodies
glucose tolerance
beta-cell function
Descripción
Sumario:Objective: We evaluated the prevalence of glutamic acid decarboxylase (GADA) and tyrosine phosphatase-protein antibodies (IA2A), their titers and their relation to first phase insulin response (FPIR) and glucose tolerance in autoimmune thyroid diseases (ATDs) patients. Subjects and methods: Graves' disease (GD