The prevalence of apical periodontitis and endodontic treatment in two coagulation disorders

Coagulation disorders such as hemophilia and Von Willebrand’s disease are characterized by changes in inflammatory responses and tissue repair. Inflammatory responses could be involved in the destruction of the periradicular bone and/or interfere with repair mechanisms following endodontic treatment...

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Detalles Bibliográficos
Autores: Andrade, Rosana Helena Teixeira de Lima Ribeiro, Encarnação, Vitor Mendes da, Dantas, Denise Gonçalves Pinho, Brasil, Sabrina Castro, Mendes, Vera Lúcia Duarte da Costa, Silva, Adriana Menucci B. da, Ferreira , Dennis de Carvalho, Pires, Fabio Ramôa, Gonçalves, Lúcio Souza, Armada, Luciana
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Federal de Itajubá (UNIFEI)
Repositorio:Research, Society and Development
Idioma:portugués
OAI Identifier:oai:ojs.pkp.sfu.ca:article/22545
Acceso en línea:https://rsdjournal.org/index.php/rsd/article/view/22545
Access Level:acceso abierto
Palabra clave:Hemophilia A
Hemophilia B
Apical periodontitis
Inflammation
von Willebrand diseases.
Enfermedades de von Willebrand
Hemofilia A
Hemofilia B
Inflamación
Periodontitis periapical.
Inflamação
Doenças de von Willebrand
Periodontite apical.
Descripción
Sumario:Coagulation disorders such as hemophilia and Von Willebrand’s disease are characterized by changes in inflammatory responses and tissue repair. Inflammatory responses could be involved in the destruction of the periradicular bone and/or interfere with repair mechanisms following endodontic treatment. The aim of this study was to evaluated the prevalence of apical periodontitis (AP) and endodontic treatment in two coagulation disorders. Panoramic radiographs (106 from the study and 106 from the control groups) were  examined for the presence of AP lesions in untreated and root canal-treated teeth. The number of teeth and the prevalence of root canal treatments were also recorded. Two endodontists evaluated all items separately. Statistical analyses were performed using the Statistical Package for Social Science (SPSS), version 21.0 (IBM, Armonk, NY, USA) and the level of statistical significance was established at 5% (p < 0.05). The prevalence of AP was not significantly different between the study and control groups (p=0.574). However, the comparative analyses between them revealed statistically significant differences in variables such as the presence of endodontic treatment (p=0.007), adequate filling (p=0.014), endodontic treatment with AP (p<0.0001), and the presence of AP in well-filled and restored teeth (p=0.003). The coagulation disorders evaluated here did not influence the manifestation of AP, however, they affected the inflammatory responses and tissue repair mechanisms.