Chemical composition and in vitro cytotoxicity of Corynespora olivacea (V18) associated with Vochysia divergens / Composição química e citotoxicidade in vitro de Corynespora olivacea (V18) associada a Vochysia divergens
Chemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extra...
| Autores: | , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Brasil |
| Institución: | Brazilian Journals Publicações de Periódicos e Editora Ltda |
| Repositorio: | Brazilian Applied Science Review |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs2.ojs.brazilianjournals.com.br:article/24414 |
| Acceso en línea: | https://ojs.brazilianjournals.com.br/ojs/index.php/BASR/article/view/24414 |
| Access Level: | acceso abierto |
| Palabra clave: | Cambará Cerrado Endophytic fungus Vochysiaceae |
| Sumario: | Chemical investigation into the ethyl acetate extract of the endophytic fungus Corynespora olivacea (V18) associated with Vochysia divergens identified compounds 1 and 2. The compounds were characterized by spectroscopic methods including NMR (1D and 2D) and HRMS. The cytotoxicity of the crude extract and the isolated compounds against normal human lung fibroblast cells, lineage GM07492A, was evaluated by the XTT assay. To the best of our knowledge, this is the first chemical and biological screening of the cytotoxicity of C. olivacea derived from V. divergens. |
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