Peritônio bovino conservado na correção de hérnia ventral em ratos: uma alternativa para tela cirúrgica biológica

OBJECTIVE: The aim of this study is to assess the tensile strength of the preserved bovine peritoneum (PBP) as a surgical mesh in rats ventral hernia. METHODS: Using 57 rats, two mesh materials, the PBP and polypropylene (PP), were compared after implantation in a standardized ventral hernia model (...

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Detalles Bibliográficos
Autores: Bastos, Eduardo Lemos de Souza [UNIFESP], Fagundes, Djalma José [UNIFESP], Taha, Murched Omar [UNIFESP], Novo, Neil Ferreira [UNIFESP], Silvado, Rubens Augusto Brazil
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2005
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/2692
Acceso en línea:http://dx.doi.org/10.1590/S0100-69912005000500007
http://repositorio.unifesp.br/handle/11600/2692
Access Level:acceso abierto
Palabra clave:Hernia, Ventral
Surgical mesh
Peritoneum
Models, Animal
Hérnia ventral
Telas cirúrgicas
Peritônio
Modelos animais
Descripción
Sumario:OBJECTIVE: The aim of this study is to assess the tensile strength of the preserved bovine peritoneum (PBP) as a surgical mesh in rats ventral hernia. METHODS: Using 57 rats, two mesh materials, the PBP and polypropylene (PP), were compared after implantation in a standardized ventral hernia model (full-thickness abdominal wall defects). After 7 (subgroup A) and 28 (subgroup B) days of implantation, they were removed and tensile strength assessment in vitro was performed. One group, with no procedure, just normal abdominal wall, was used as control for tensile strength. The Mann-Whitney and Kruskal- Wallis tests were applied for statistical analysis. RESULTS: All animals survived until the end point, but one (PBP group, subgroup B). No recurrence was seen during the period of observation. The mean load required to disrupt the interface were similar in PBP and PP groups, and both were weaker than normal group (p = 0,003) in all periods of observation. CONCLUSION: Preserved bovine peritoneum is a biological mesh that can be used for ventral hernia repair in rat model.