Falência primária pós-transplante de córnea em serviço universitário

Purpose: To analyze the factors related to primary corneal graft failure after penetrating keratoplasty in the Corneal and External Diseases Section of the Federal University of São Paulo, Brazil. Methods: A retrospective study was performed using the charts of patients submitted to penetrating kera...

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Bibliographic Details
Authors: Hirai, Flávio Eduardo [UNIFESP], Klatte, Stefan, Pacini, Keila Mattos [UNIFESP], Sato, Elcio Hideo [UNIFESP]
Format: article
Status:Published version
Publication Date:2002
Country:Brasil
Institution:Universidade Federal de São Paulo (UNIFESP)
Repository:Repositório Institucional da UNIFESP
Language:Portuguese
OAI Identifier:oai:repositorio.unifesp.br:11600/1560
Online Access:http://dx.doi.org/10.1590/S0004-27492002000600011
http://repositorio.unifesp.br/handle/11600/1560
Access Level:Open access
Keyword:Corneal transplantation
Eye banks
Corneal diseases
Tissue preservation
Transplante de córnea
Bancos de olhos
Doenças da córnea
Preservação de tecido
Description
Summary:Purpose: To analyze the factors related to primary corneal graft failure after penetrating keratoplasty in the Corneal and External Diseases Section of the Federal University of São Paulo, Brazil. Methods: A retrospective study was performed using the charts of patients submitted to penetrating keratoplasty from July 1999 to March 2001. Cases of primary failure (group I) and patients submitted to the surgical procedure at the same period (group II) were selected and compared. Information collected from donors were age, cause of death, endothelial cell count, time between death and enucleation (T1), time between enucleation and preservation of the graft (T2) and time of tissue preservation until surgery (T3). Results: 164 patients were analyzed with 21 cases of primary failure (12.8%). The mean age of the donors of group I was 43.1 years (±22.0) and from group II was 47.9 years (±18.9). There was no statistical difference between the two groups considering the time intervals (T1, T2, T3). Causes of death included trauma, cancer and heart diseases. Conclusion: Differences in all analyzed factors were not significant between both groups. The difficulties in determining the causes of primary corneal graft failure suggests a multifactorial process involved in this problem. Well-trained Eye Bank staff and notifications about postoperative complications are important to decrease the primary failure incidence.