Neurofibromatosis type 1, fibromuscular dysplasia, and ischemic stroke: an association lost in time? A case report

Neurofibromatosis Type 1 (NF1) is a rare cause of ischemic stroke (IS) in the general population. We report a case of a young patient with NF1 in whom IS was caused by fibromuscular dysplasia. An angiographic study demonstrated occlusion in the right internal carotid artery (ICA), just after its ori...

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Detalles Bibliográficos
Autores: Fonseca, Igor Oliveira Da [UNESP], Luvizutto, Gustavo José, Souza, Isaac Pantaleão [UNESP], Trindade, André Petean [UNESP], Freitas, Carlos Clayton Macedo De [UNESP], Bazan, Rodrigo, Modolo, Gabriel Pinheiro [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/244926
Acceso en línea:http://dx.doi.org/10.1590/1677-5449.202201182
http://hdl.handle.net/11449/244926
Access Level:acceso abierto
Palabra clave:neurofibromatosis type 1
fibromuscular dysplasia
stroke
neurofibromatose tipo 1
displasia fibromuscular
acidente vascular encefálico
Descripción
Sumario:Neurofibromatosis Type 1 (NF1) is a rare cause of ischemic stroke (IS) in the general population. We report a case of a young patient with NF1 in whom IS was caused by fibromuscular dysplasia. An angiographic study demonstrated occlusion in the right internal carotid artery (ICA), just after its origin, and the left ICA, just before the intracranial portion, and brain magnetic resonance imaging showed the limits of an area of brain infarction in the right frontoparietal region. Despite these concomitant neuroimaging findings, this association is rare, and it is difficult to establish the contribution to the outcome made by each of these diseases, which treatment is the best to implement, or what prognosis is.