A specific polymerase chain reaction method to identify Stenotrophomonas maltophilia

Stenotrophomonas maltophilia is a multidrug-resistant nosocomial pathogen that is difficult to identify unequivocally using current methods. Accordingly, because the presence of this microorganism in a patient may directly determine the antimicrobial treatment, conventional polymerase chain reaction...

Full description

Bibliographic Details
Authors: Gallo, Stephanie Wagner, Ramos, Patricia Locosque, Ferreira, Carlos Alexandre Sanchez, Oliveira, Silvia Dias de
Format: article
Status:Published version
Publication Date:2013
Country:Brasil
Institution:Universidade Federal de São Paulo (UNIFESP)
Repository:Repositório Institucional da UNIFESP
Language:English
OAI Identifier:oai:repositorio.unifesp.br:11600/7738
Online Access:http://dx.doi.org/10.1590/S0074-02762013000300020
http://repositorio.unifesp.br/handle/11600/7738
Access Level:Open access
Keyword:Stenotrophomonas maltophilia
identification
PCR
Description
Summary:Stenotrophomonas maltophilia is a multidrug-resistant nosocomial pathogen that is difficult to identify unequivocally using current methods. Accordingly, because the presence of this microorganism in a patient may directly determine the antimicrobial treatment, conventional polymerase chain reaction (PCR) and real-time PCR assays targeting 23S rRNA were developed for the specific identification of S. maltophilia. The PCR protocol showed high specificity when tested against other species of Stenotrophomonas, non-fermentative Gram-negative bacilli and 100 clinical isolates of S. maltophilia previously identified using the Vitek system.