Midazolam versus diazepam for the treatment of status epilepticus in pediatric emergency Abstract in English
AIMS: To conduct a review article evaluating midazolam administered by different routes as well as diazepam administered through intravenous and rectal route for treating status epilepticus in children. SOURCE OF DATA: Bibliographic search was conducted on Google Scholar, LILACS, PubMed and SciELO d...
| Autores: | , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2011 |
| País: | Brasil |
| Recursos: | Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) |
| Repositorio: | Scientia Medica (Porto Alegre. Online) |
| Idioma: | portugués inglés |
| OAI Identifier: | oai:ojs.revistaseletronicas.pucrs.br:article/9176 |
| Acesso em linha: | https://revistaseletronicas.pucrs.br/scientiamedica/article/view/9176 |
| Access Level: | acceso abierto |
| Palavra-chave: | EPILEPSY/drug therapy ANTICONVULSANTS/administration & dosage MIDAZOLAM DIAZEPAM EMERGENCIES EMERGENCY SERVICE HOSPITAL PEDIATRICS CHILD PRESCHOOL INFANT. EPILEPSIA/quimioterapia ANTICONVULSIVANTES/administração & dosagem EMERGÊNCIAS SERVIÇO HOSPITALAR DE EMERGÊNCIA PEDIATRIA CRIANÇA PRÉ-ESCOLAR LACTENTE. |
| Resumo: | AIMS: To conduct a review article evaluating midazolam administered by different routes as well as diazepam administered through intravenous and rectal route for treating status epilepticus in children. SOURCE OF DATA: Bibliographic search was conducted on Google Scholar, LILACS, PubMed and SciELO databases, using the key words status epilepticus, seizure, benzodiazepines, midazolam, diazepam, children. SUMMARY OF FINDINGS: Rapid onset treatment of status epilepticus is associated with better results. Diazepam has been the first-line treatment in the last 30 years, despite of known difficulties of venipuncture in infants. Midazolam appears to be an important advance for the quick seizure emergency treatment for its ease administration and rapid action. The ideal drug and route of administration for seizure control in these situations remain uncertain. CONCLUSIONS: If intravenous access is not available, there is evidence that intramuscular, oral or nasal midazolam can be an alternative to diazepam (rectal or intravenous) for treatment of seizures in pediatric emergency. |
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