Pioderma gangrenoso bolhoso e síndrome mielodisplásica

Pyoderma gangrenosum can present as a cutaneous manifestation of paraneoplastic syndromes. A case of bullous pyoderma gangrenosum associated with bicytopenia is described. During the complementary investigation, myelogram, bone marrow biopsy and karyotype were performed, and showed a pattern consist...

Descripción completa

Detalles Bibliográficos
Autores: Batista, Mariana Dias [UNIFESP], Fernandes, Ricardo Limongi [UNIFESP], Rocha, Marco Alexandre Dias Da [UNIFESP], Ikino, Juliana Kida [UNIFESP], Pinheiro, Ronald Feitosa [UNIFESP], Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP], Michalany, Nílceo Schwery [UNIFESP], Almeida, Fernando Augusto De [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/3274
Acceso en línea:http://dx.doi.org/10.1590/S0365-05962006000900013
http://repositorio.unifesp.br/handle/11600/3274
Access Level:acceso abierto
Palabra clave:Autoimmune diseases
Dapsone
Myelodysplastic syndromes
Pyoderma gangrenosum
Dapsona
Doenças auto-imunes
Pioderma gangrenoso
Síndromes mielodisplásicas
Descripción
Sumario:Pyoderma gangrenosum can present as a cutaneous manifestation of paraneoplastic syndromes. A case of bullous pyoderma gangrenosum associated with bicytopenia is described. During the complementary investigation, myelogram, bone marrow biopsy and karyotype were performed, and showed a pattern consistent with myelodysplastic syndrome. The patient was treated with dapsone with improvement. Pyoderma gangrenosum can be a manifestation of systemic diseases. The possibility of myelodysplastic syndrome should always be considered in patients with pyoderma gangrenosum associated with cytopenia. Pyoderma gangrenosum could indicate poorer prognosis in patients with systemic diseases.