IL-10 gene polymorphism in elderly with periodontal disease
Introduction: Genetic factors contribute to the risk of periodontal disease (PD) in the elderly. Objective: This study aimed to evaluate the association between periodontal disease and interleukin-10 gene polymorphism in 66 elderly. Methods: PD was diagnosed using the index PIP. The genetic polymorp...
| Autores: | , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Brasil |
| Institución: | Universidade Nove de Julho (UNINOVE) |
| Repositorio: | Revista Conscientiae Saúde (Online) |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.periodicos.uninove.br:article/3423 |
| Acceso en línea: | https://periodicos.uninove.br/saude/article/view/3423 |
| Access Level: | acceso abierto |
| Palabra clave: | Elderly Interleukin-10 Periodontal diseases Polymorphism genetic. Doenças periodontais Idoso Interleucina-10 Polimorfismo genético. |
| Sumario: | Introduction: Genetic factors contribute to the risk of periodontal disease (PD) in the elderly. Objective: This study aimed to evaluate the association between periodontal disease and interleukin-10 gene polymorphism in 66 elderly. Methods: PD was diagnosed using the index PIP. The genetic polymorphism was analyzed by polymerase chain reaction followed by cleavage with restriction enzyme Rsa I. Results: The study included 66 elderly (mean age: 68 ± 5.02 years), 63.3% female gender and 36.4% male. The elderly harboring AA genotype or A allele were significantly associated with severe PD, according to 2 test (p |
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