Auriculotherapy to control chemotherapy-induced nausea and vomiting in patients with cancer: protocol of a systematic review

Background: Due to the worldwide rise in cancer incidence, and therefore the rise in the need for antineoplastic chemotherapy, it is important for both healthcare professionals and patients alike that the side effects of chemotherapy, such as chemotherapy-induced nausea and vomiting (CINV), are trea...

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Detalhes bibliográficos
Autores: Ruan Nilton Rodrigues Melo, Stephanie Carolina Francisco, Caroline de Castro Moura, Kirsty Loudon, Namie Okino Sawada, Érika de Cássia Lopes Chaves, Tânia Couto Machado Chianca, Denismar Alves Nogueira, Si Jia Zhu, Ana Cláudia Mesquita Garcia
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Recursos:Universidade Federal de Minas Gerais (UFMG)
Repositorio:Repositório Institucional da UFMG
Idioma:inglés
OAI Identifier:oai:repositorio.ufmg.br:1843/53605
Acesso em linha:https://doi.org/10.1186/s13643-019-1124-3
http://hdl.handle.net/1843/53605
https://orcid.org/0000-0003-1224-7177
https://orcid.org/0000-0002-4449-6226
https://orcid.org/0000-0002-1874-3481
https://orcid.org/0000-0002-2346-5359
http://orcid.org/0000-0002-8313-2791
https://orcid.org/0000-0003-2285-8764
https://orcid.org/0000-0001-6508-4979
https://orcid.org/0000-0001-9793-7905
Access Level:acceso abierto
Palavra-chave:Nausea
Vomiting
Drug therapy
Neoplasms
Auricular acupuncture
Systematic review
Náusea
Vômito
Tratamento Farmacológico
Neoplasias
Acupuntura Auricular
Descrição
Resumo:Background: Due to the worldwide rise in cancer incidence, and therefore the rise in the need for antineoplastic chemotherapy, it is important for both healthcare professionals and patients alike that the side effects of chemotherapy, such as chemotherapy-induced nausea and vomiting (CINV), are treated and prevented. Auriculotherapy is a type of acupuncture and may be a low-cost and safe antiemetic measure to control the side effects of chemotherapy. The goal of this systematic review is to synthesize the available evidence in the literature regarding the auriculotherapy effects to treat CINV in people with cancer. Methods: The review will only include randomized controlled trials (RCTs) that compare the clinical effects of the auriculotherapy intervention (used alone or as an add-on), with sham auriculotherapy, routine treatment with antiemetic drugs, or other non-pharmacological interventions in patients with cancer with CINV who are undergoing chemotherapy. The outcomes to be evaluated are nausea and vomiting: in acute, delayed, or anticipated stages, when induced by chemotherapy. A comprehensive search for studies will be carried out in these databases: MEDLINE via PubMed, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, ICTRP, LILACS, CUMED, IBECS, BVS MTCI Americas, Web of Science, Scopus, PEDro, CNKI, and CBMdisc up until December 31, 2018. Only articles in English, Portuguese, and Spanish will be selected. Two independent reviewers will evaluate full texts, extract data, and assess the risk of bias of eligible articles. The quality of evidence will be assessed using Grading of Recommendations, Assessment, Development and Evaluation (GRADE). A meta-analysis will be undertaken to assess the interventions and outcomes’ homogeneity, assessing statistical heterogeneity using the Cochran’s Q test and quantified using Higgins’ inconsistency index. If there is insufficient data for a meta-analysis, a narrative synthesis will be presented. This protocol has been prepared according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines. Discussion: The results of this systematic review will summarize the strength of evidence for the use of auriculotherapy in the control of CINV of patients with cancer and will be used to identify evidence gaps.