Tratamento multidisciplinar reduz o tecido adiposo visceral, leptina, grelina e a prevalência de esteatose hepática não alcoólica (NAFLD) em adolescentes obesos

The aim of this study was to assess the changes promoted by a multidisciplinary therapy in ghrelin and leptin concentrations, visceral adiposity and non-alcoholic fat liver disease-NAFLD, in obese adolescents. A total of 28 obese adolescents, 16 girls (BMI 34.58 ± 3,86 wt/ht²) and 12 boys (BMI 37.08...

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Detalles Bibliográficos
Autores: Dâmaso, Ana Raimunda [UNIFESP], Tock, Lian [UNIFESP], Tufik, Sergio [UNIFESP], Prado, Wagner Luiz do [UNIFESP], Stella, Sérgio Garcia [UNIFESP], Fisberg, Mauro [UNIFESP], Cintra, Isa de Pádua [UNIFESP], Caranti, Danielle Arisa [UNIFESP], Siqueira, Kãli O. [UNIFESP], Nascimento, Claudia Maria da Penha Oller do [UNIFESP], Oyama, Lila Missae [UNIFESP], Lederman, Henrique Manoel [UNIFESP], Cristofalo, Dejaldo [UNIFESP], Antunes, Hanna Karen Moreira [UNIFESP], Comparoni, Aniella [UNIFESP], Santos, Luana Caroline dos [UNIFESP], Mello, Marco Tulio de [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/3285
Acceso en línea:http://dx.doi.org/10.1590/S1517-86922006000500008
http://repositorio.unifesp.br/handle/11600/3285
Access Level:acceso abierto
Palabra clave:Obesity
Life-style
Leptin
Ghrelin
Non-alcoholic fat liver disease
Obesidade
Estilo de vida
Leptina
Grelina
Esteatose hepática não alcoólica
Descripción
Sumario:The aim of this study was to assess the changes promoted by a multidisciplinary therapy in ghrelin and leptin concentrations, visceral adiposity and non-alcoholic fat liver disease-NAFLD, in obese adolescents. A total of 28 obese adolescents, 16 girls (BMI 34.58 ± 3,86 wt/ht²) and 12 boys (BMI 37.08 ± 3.17 wt/ht²), aged between 15 and 19 years old, was evaluated to leptin, ghrelin and insulin concentrations, visceral adiposity and NAFLD through ultrasonography. The results showed a significant decrease in ghrelin, leptin concentrations and visceral adiposity (p < 0.01). Moreover, a decrease in the NAFLD prevalence was observed. It is an important result, since this disease can progress to cirrhosis, not only in children but also in obese adolescents. This kind of treatment can be efficient to improve metabolic and hormonal profile, as well as, to control obesity and related co-morbidities in obese adolescents.

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