Avaliação morfológica da aterosclerose nas artérias aortas, carótidas e ilíacas de pacientes autopsiados
Artigo 1 - Osteoid metaplasia with functioning marrow is a rare pathological process in arterial calcifications, associated to the asymptomatic development of atherosclerotic plaques. Objective: To describe morphological aspects of bone metaplasia in arterial calcifications and its pathogenesis in t...
| Autor: | |
|---|---|
| Tipo de recurso: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | Brasil |
| Institución: | Universidade Federal do Triangulo Mineiro (UFTM) |
| Repositorio: | Biblioteca Digital de Teses e Dissertações da UFTM |
| Idioma: | portugués |
| OAI Identifier: | oai:bdtd.uftm.edu.br:123456789/1302 |
| Acceso en línea: | http://bdtd.uftm.edu.br/handle/123456789/1302 |
| Access Level: | acceso abierto |
| Palabra clave: | CNPQ::CIENCIAS BIOLOGICAS::MORFOLOGIA::CITOLOGIA E BIOLOGIA CELULAR Autopsy. Bone marrow. Calcinosis. Iliac artery. Aterosclerose. Artérias. Autopsia. Autópsia. Morfometria. Artéria. |
| Sumario: | Artigo 1 - Osteoid metaplasia with functioning marrow is a rare pathological process in arterial calcifications, associated to the asymptomatic development of atherosclerotic plaques. Objective: To describe morphological aspects of bone metaplasia in arterial calcifications and its pathogenesis in two cases. Macroscopic examination of iliac arteries was performed and fragments of approximately 2 cm of the right and left iliac arteries were collected for microscopic analysis of atherosclerosis. These fragments were processed histologically and stained with hematoxylin and eosin (HE). A pronounced atherosclerosis, characterized by diffuse atheroma plaques and foci of calcifications, was evidenced. In both cases, in intima layer of atherosclerotic plaque in right iliac artery, a dilatation, and the presence of bone metaplasia with bone trabeculae, calcifications, and functioning bone marrow with red blood cells and megakaryocytes were observed. Due to the rarity of this lesion, its description allows better characterization of morphological data and pathogenesis. |
|---|