Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)

Tambaqui (Colossoma macropomum) are a model species for tropical fish physiology, but details are lacking about their ionoregulatory response to acid waters. To provide specifics, we measured unidirectional Na+ fluxes in low pH waters. Sodium influx (JinNa) was uninhibited during acute exposure to p...

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Detalles Bibliográficos
Autores: Gonzalez, R. J., Patrick, M. L., Duarte, R. M. [UNESP], Casciato, A., Thackeray, J., Day, N., Val, A. L.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/205887
Acceso en línea:http://dx.doi.org/10.1007/s00360-021-01349-x
http://hdl.handle.net/11449/205887
Access Level:acceso abierto
Palabra clave:Fish
Ion regulation
Low pH
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spelling Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)FishIon regulationLow pHTambaqui (Colossoma macropomum) are a model species for tropical fish physiology, but details are lacking about their ionoregulatory response to acid waters. To provide specifics, we measured unidirectional Na+ fluxes in low pH waters. Sodium influx (JinNa) was uninhibited during acute exposure to pH 4.5 and 3.5, and Na efflux (JoutNa) rose only slightly at pH 3.5; net Na+ flux (JnetNa) remained positive at all pH. Similarly, during 24 h transfer to pH 3.5 JinNa, JoutNa, and JnetNa were unchanged at all times. Taking a closer look at the mechanism of Na+ transport in the gills of tambaqui we found that JinNa was uninhibited by HMA, a Na+/H+-exchanger blocker, and Benzamil, a Na+-channel inhibitor, casting doubt on their role in Na+ uptake in this fish. Measurement of Na+/K+-ATPase (NKA) and H+-ATPase (VHA) activity showed that neither changed at low pH compared to measurements at pH 6.5. Western blot analysis of ATPase expression saw no changes in amount of NKA and VHA at low pH, and immunohistochemistry showed expression of both NKA and VHA on lamellae and interlamellar region of tambaqui gills and that both proteins co-localized to the same gill cells. Location of expression also did not change in low pH water. Amazingly, tambaqui seem unaffected by pH 3.5 water, making them one of the most acid-tolerant fish species examined so far. In addition, they appear to share key ionoregulatory traits with other fish of the order Characiformes, which suggest a common origin for the ionoregulatory attributes.Department of Biology University of San Diego, 5998 Alcalá ParkBiosciences Institute São Paulo State University-UNESP, Coastal CampusLaboratório de Ecofisiologia e Evolução Molecular Instituto Nacional de Pesquisas da Amazônia (INPA)Division of Biological Sciences University of MontanaBiosciences Institute São Paulo State University-UNESP, Coastal CampusUniversity of San DiegoUniversidade Estadual Paulista (Unesp)Instituto Nacional de Pesquisas da Amazônia (INPA)University of Montana2021-06-25T10:22:57Z2021-06-25T10:22:57Z2021-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article493-502http://dx.doi.org/10.1007/s00360-021-01349-xJournal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, v. 191, n. 3, p. 493-502, 2021.0174-1578http://hdl.handle.net/11449/20588710.1007/s00360-021-01349-x2-s2.0-85100872631Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiologyinfo:eu-repo/semantics/openAccessGonzalez, R. J.Patrick, M. L.Duarte, R. M. [UNESP]Casciato, A.Thackeray, J.Day, N.Val, A. L.2025-04-11T19:38:34Zoai:repositorio.unesp.br:11449/205887Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462025-04-11T19:38:34Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
title Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
spellingShingle Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
Gonzalez, R. J.
Fish
Ion regulation
Low pH
title_short Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
title_full Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
title_fullStr Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
title_full_unstemmed Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
title_sort Exposure to pH 3.5 water has no effect on the gills of the Amazonian tambaqui (Colossoma macropomum)
dc.creator.none.fl_str_mv Gonzalez, R. J.
Patrick, M. L.
Duarte, R. M. [UNESP]
Casciato, A.
Thackeray, J.
Day, N.
Val, A. L.
author Gonzalez, R. J.
author_facet Gonzalez, R. J.
Patrick, M. L.
Duarte, R. M. [UNESP]
Casciato, A.
Thackeray, J.
Day, N.
Val, A. L.
author_role author
author2 Patrick, M. L.
Duarte, R. M. [UNESP]
Casciato, A.
Thackeray, J.
Day, N.
Val, A. L.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv University of San Diego
Universidade Estadual Paulista (Unesp)
Instituto Nacional de Pesquisas da Amazônia (INPA)
University of Montana
dc.subject.por.fl_str_mv Fish
Ion regulation
Low pH
topic Fish
Ion regulation
Low pH
description Tambaqui (Colossoma macropomum) are a model species for tropical fish physiology, but details are lacking about their ionoregulatory response to acid waters. To provide specifics, we measured unidirectional Na+ fluxes in low pH waters. Sodium influx (JinNa) was uninhibited during acute exposure to pH 4.5 and 3.5, and Na efflux (JoutNa) rose only slightly at pH 3.5; net Na+ flux (JnetNa) remained positive at all pH. Similarly, during 24 h transfer to pH 3.5 JinNa, JoutNa, and JnetNa were unchanged at all times. Taking a closer look at the mechanism of Na+ transport in the gills of tambaqui we found that JinNa was uninhibited by HMA, a Na+/H+-exchanger blocker, and Benzamil, a Na+-channel inhibitor, casting doubt on their role in Na+ uptake in this fish. Measurement of Na+/K+-ATPase (NKA) and H+-ATPase (VHA) activity showed that neither changed at low pH compared to measurements at pH 6.5. Western blot analysis of ATPase expression saw no changes in amount of NKA and VHA at low pH, and immunohistochemistry showed expression of both NKA and VHA on lamellae and interlamellar region of tambaqui gills and that both proteins co-localized to the same gill cells. Location of expression also did not change in low pH water. Amazingly, tambaqui seem unaffected by pH 3.5 water, making them one of the most acid-tolerant fish species examined so far. In addition, they appear to share key ionoregulatory traits with other fish of the order Characiformes, which suggest a common origin for the ionoregulatory attributes.
publishDate 2021
dc.date.none.fl_str_mv 2021-06-25T10:22:57Z
2021-06-25T10:22:57Z
2021-05-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1007/s00360-021-01349-x
Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, v. 191, n. 3, p. 493-502, 2021.
0174-1578
http://hdl.handle.net/11449/205887
10.1007/s00360-021-01349-x
2-s2.0-85100872631
url http://dx.doi.org/10.1007/s00360-021-01349-x
http://hdl.handle.net/11449/205887
identifier_str_mv Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology, v. 191, n. 3, p. 493-502, 2021.
0174-1578
10.1007/s00360-021-01349-x
2-s2.0-85100872631
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 493-502
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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