PROD and BROD modulation in Nile tilapia after exposure to 17 beta-estradiol

The activities of 7-ethoxyresorufin-O-deetylase (EROD), 7-benzyloxyresorufin-O-debenzylase (BROD), 7-pentoxyresorufin-O-depentilase (PROD), and glutathione S-transferase (GST) were measured in Nile tilapias exposed for 7 days of 5 and 15 μg/L 17 β-estradiol. EROD and GST activities were unchanged. P...

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Detalhes bibliográficos
Autores: Bitencourt, Franciele [UNESP], Frighetto, Rosa Toyoko Shiraishi, Queiroz, Julio Ferraz de, Losekann, Marcos Eliseu, Luiz, Afonso Jose Barreto, Almeida, Eduardo Alves de [UNESP]
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/122480
Acesso em linha:http://www.davidpublishing.com/show.html?408
http://hdl.handle.net/11449/122480
Access Level:acceso abierto
Palavra-chave:EROD
PROD
BROD
17 beta-estradiol
biomaker
Nile tilapia
Descrição
Resumo:The activities of 7-ethoxyresorufin-O-deetylase (EROD), 7-benzyloxyresorufin-O-debenzylase (BROD), 7-pentoxyresorufin-O-depentilase (PROD), and glutathione S-transferase (GST) were measured in Nile tilapias exposed for 7 days of 5 and 15 μg/L 17 β-estradiol. EROD and GST activities were unchanged. PROD activity increased in animals exposed to the higher dose of the hormone, while BROD was increased after 7 exposure days to both doses of the compound. These results indicate the usefulness of these enzymes as biomarkers for 17 β-estradiol exposure.

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