Post-kidney transplant Whipple’s disease: a case report and literature review
After more than one hundred years of the description on the Whipple’s disease by George H. Whipple, the diagnosis, pathogenesis and treatment still remain controversial. It is rare disease caused by the Tropheryma whipplei bacterium, which is also found in the environment without causing any damage....
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2010 |
| País: | Brasil |
| Institución: | Associação Brasileira de Transplante de Órgãos (ABTO) |
| Repositorio: | Brazilian Journal of Transplantation |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs3.emnuvens.com.br:article/241 |
| Acceso en línea: | https://bjt.emnuvens.com.br/revista/article/view/241 |
| Access Level: | acceso abierto |
| Palabra clave: | Transplante Renal Doença de Whipple Tropheryma Whipplei Kidney Transplantation Whipple Desease |
| Sumario: | After more than one hundred years of the description on the Whipple’s disease by George H. Whipple, the diagnosis, pathogenesis and treatment still remain controversial. It is rare disease caused by the Tropheryma whipplei bacterium, which is also found in the environment without causing any damage. Symptoms are nonspecific, such as diarrhea, arthralgia, and weakness; it may present severe cardiac symptoms and in the central nervous system. The most accurate diagnosis is performed by PCR (polymerase chain reaction) and immunohistochemistry, but they are poorly disseminated. Treatment is with intravenous ceftriaxone followed by trimethoprim-sulfamethoxazole for two years. Below, this article describes a case of Whipple’s disease after renal transplantation, which the authors believe to be the second case reported in literature. |
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