Kharon Is Crucial for Trypanosoma cruzi Morphology but Does Not Impair In Vitro Infection

The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/pathogens14040312/s1, Figure S1: Multiple alignment of TcKharon orthologs and identity matrix; Figure S2: Structure prediction and protein sequence alignment of Kharon orthologs; Figure S3: PONDR® predict...

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Bibliographic Details
Authors: Saenz-Garcia, Jose Luis Saenz-Garcia, Souza-Melo, Normanda, Miranda, Juliana Severo, Borges, Beatriz, Pacheco-Lugo, Lisandro A., Quintero-Solano, Jose M., Moretti, Nilmar, Wheeler, Richard, Soares-Medeiros, Lia C., DaRocha, Wanderson D.
Format: article
Status:Published version
Publication Date:2025
Country:Brasil
Institution:Fundação Oswaldo Cruz (FIOCRUZ)
Repository:Repositório Institucional da FIOCRUZ (ARCA)
Language:English
OAI Identifier:oai:arca.fiocruz.br:icict/73759
Online Access:https://arca.fiocruz.br/handle/icict/73759
Access Level:Open access
Keyword:Trypanosoma cruzi
morfologia
CRISPR/Cas9
Description
Summary:The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/pathogens14040312/s1, Figure S1: Multiple alignment of TcKharon orthologs and identity matrix; Figure S2: Structure prediction and protein sequence alignment of Kharon orthologs; Figure S3: PONDR® prediction (A–E), proline and charged amino acids compositions (F) of Kharon orthologs.; Figure S4: TEM images of TcKharon−/− mutant cells with 2N1K configuration; Figure S5: Analysis of fluorescence of the TcKharon-AB cells [46,47].

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