Experimental model of cranially pedicled TRAM flap in rats

In a simple, reproducible, and non-expensive experimental model the transverse rectus abdominis muscle (TRAM) flap has been described in male, adult Wistar rats (Rattus norvegicus albinus, Rodentia, Mammalia), weighing approximately 300g, at the central biotery of the Federal University at São Paulo...

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Detalles Bibliográficos
Autores: Garcia, Elvio Bueno [UNIFESP], Ferreira, Lydia Masako [UNIFESP], Sabino Neto, Miguel [UNIFESP], Sallum, Natasha [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2004
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:inglés
OAI Identifier:oai:repositorio.unifesp.br:11600/2300
Acceso en línea:http://dx.doi.org/10.1590/S0102-86502004000700011
http://repositorio.unifesp.br/handle/11600/2300
Access Level:acceso abierto
Palabra clave:Rats
TRAM flap
Tissue Survival
Models, Animal
Ratos
Retalho TRAM
Modelos Animais
Sobrevivência tecidual
Descripción
Sumario:In a simple, reproducible, and non-expensive experimental model the transverse rectus abdominis muscle (TRAM) flap has been described in male, adult Wistar rats (Rattus norvegicus albinus, Rodentia, Mammalia), weighing approximately 300g, at the central biotery of the Federal University at São Paulo, Paulista Medical School (UNIFESP - EPM). This article describes the use of a cranially based pedicled rectus abdominis muscle flap sling, unilaterally to the right, with the purpose to better understand the pathophysiology of and the research on new treatments to prevent partial or total flap necrosis. This experimental model sponsors quite a number of studies to be conducted to assess the effects of different drugs of physical methods on the feasibility of standard, cranial monopedicled TRAM.As a standard model, it also harbors the comparison among results from different studies.