Sarcopenia, bone mineral density, and vitamin D: EpiFloripa aging study 2013/2014
<p><b>OBJECTIVE:</b> To verify associations between osteopenia/osteoporosis and vitamin D and sarcopenia in the older adult population of Florianópolis, Brazil.<br> <b>METHODS:</b> A cross-sectional population-based study, with 604 older adults (60 years and over)...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2020 |
| País: | Brasil |
| Institución: | Sociedade Brasileira de Geriatria e Gerontologia |
| Repositorio: | Geriatrics, Gerontology and Aging (Online) |
| Idioma: | inglés |
| OAI Identifier: | oai:ggaging.com:1659 |
| Acceso en línea: | https://ggaging.com/details/1659 |
| Access Level: | acceso abierto |
| Palabra clave: | sarcopenia osteoporosis bone diseases, metabolic aged. |
| Sumario: | <p><b>OBJECTIVE:</b> To verify associations between osteopenia/osteoporosis and vitamin D and sarcopenia in the older adult population of Florianópolis, Brazil.<br> <b>METHODS:</b> A cross-sectional population-based study, with 604 older adults (60 years and over). The appendicular muscle mass index (AMMI) was used to identify sarcopenia, with cutoffs of AMMI (Kg/m<sup>2</sup>) < 7.26 kg/m<sup>2</sup> for men and < 5.50 kg/m<sup>2</sup> for women indicating inadequate values (sarcopenia). The independent variable osteopenia/osteoporosis was measured using bone mineral density (BMD, g/cm<sup>2</sup>): T-Scores for whole body BMD, lumbar spine BMD, and femoral neck BMD, categorized as normal (BMD > -1 SD) or osteopenia/osteoporosis (BMD < -1 SD from the mean of the young adult reference population). Fasting serum samples were collected and assayed using the microparticle chemiluminescence (CMIA)/Liaison method. Vitamin D concentrations of < 30 ng/mL were defined as hypovitaminosis. Crude and adjusted logistic regression analyses were performed.<br> <b>RESULTS:</b> Osteopenia/osteoporosis in the lumbar spine and femoral neck were associated with higher odds of sarcopenia in women and men. Osteopenia/osteoporosis in the whole body was associated with sarcopenia in women only. Vitamin D was not associated with sarcopenia in either sex.<br> <b>CONCLUSIONS:</b> Having osteopenia/osteoporosis was associated with sarcopenia in this older adult population.</p> |
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