Pierre Robin sequence: Case report, the relevance of autopsy

Pierre Robin sequence is a neonatal disorder characterized by micrognathism, glossoptosis and cleft palate. We reported an autopsy case of a child whose malformations of the oropharynx were identified only at birth. The child was extremely preterm with severe neonatal depression and poor recovery, a...

Descripción completa

Detalles Bibliográficos
Autores: Oliveira, Cristiano C. [UNESP], Domingues, Maria Aparecida C. [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/172245
Acceso en línea:http://dx.doi.org/10.5935/1676-2444.20150054
http://hdl.handle.net/11449/172245
Access Level:acceso abierto
Palabra clave:Autopsy
Pathology
Pierre Robin syndrome
Descripción
Sumario:Pierre Robin sequence is a neonatal disorder characterized by micrognathism, glossoptosis and cleft palate. We reported an autopsy case of a child whose malformations of the oropharynx were identified only at birth. The child was extremely preterm with severe neonatal depression and poor recovery, and the orofacial alterations prevented the correct treatment. There was facial disorder characterized by micrognathia associated with cleft palate and posterior displacement of the tongue, compressing the vallecula, structurally compatible with glossoptosis. This autopsy surpassed the scientific and epidemiological relevance, allowing the family genetic counseling and close monitoring of a subsequent pregnancy.