Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study

Background: Dentin hypersensitivity affects a significant portion of the world’s population, causing pain and negatively impacting oral health and quality of life This clinical study investigated the effectiveness of a desensitizing fluoride silicon-rich dental gel associated with a calcium booster....

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Autores: Fernandes, Leandro Araújo, Reis, Ana Luíza Marques, de Cássia dos Reis, Marcela, Mazzola, Thamires, da Cruz Pegoraro, João Vitor, Neto, Sebastião Orestes Pereira, de Lima, Daniela Coelho, D’Alpino, Paulo Henrique Perlatti [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/302285
Acceso en línea:http://dx.doi.org/10.4317/jced.62205
https://hdl.handle.net/11449/302285
Access Level:acceso abierto
Palabra clave:Clinical trial
dentin hypersensitivity
desensitizing
toothpaste
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spelling Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical studyClinical trialdentin hypersensitivitydesensitizingtoothpasteBackground: Dentin hypersensitivity affects a significant portion of the world’s population, causing pain and negatively impacting oral health and quality of life This clinical study investigated the effectiveness of a desensitizing fluoride silicon-rich dental gel associated with a calcium booster. Material and Methods: In this single-blind, randomized, parallel-group clinical trial, forty-eight volunteers diagnosed with dentin hypersensitivity and qualified to participate were randomized into 2 groups: (1) fluoride silicon-rich dental gel (REFX Technology)/calcium booster (Si/Ca protocol); (2) Pumice stone diluted in saline. A draw was carried out between the right and left sides of the patients so that either a prophylaxis with the dental gel associated with calcium or with fine pumice stone diluted in saline was carried out. An evaporative test was used to check for dentin hypersensitivity in the subjects before and immediately after treatment and scored using the Schiff scale, rated 0 to 3. Data were statistically analyzed (ANOVA/Tukey test, α=5%). Results: The treatment with Si/Ca protocol drastically reduced dentin hypersensitivity (from 2.58 to 0.67) immediately after the use. In the control group (Pumice stone), similar results were observed before and after treatment (2.67 and 2.82, respectively). Conclusions: The Si/Ca protocol was fast and effective in reducing pain caused by dentin hypersensitivity.School of Dentistry Universidade Federal de Alfenas (UNIFALMG), Minas GeraisTriplet Biotechnology Solutions Inc., SPSão Paulo State University (UNESP) School of Sciences, SPSão Paulo State University (UNESP) School of Sciences, SPUniversidade Federal de Alfenas (UNIFALMG)Inc.Universidade Estadual Paulista (UNESP)2025-04-29T19:14:08Z2024-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlee1475-e1480http://dx.doi.org/10.4317/jced.62205Journal of Clinical and Experimental Dentistry, v. 16, n. 12, p. e1475-e1480, 2024.1989-5488https://hdl.handle.net/11449/30228510.4317/jced.622052-s2.0-85211142938Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Clinical and Experimental Dentistryinfo:eu-repo/semantics/openAccessFernandes, Leandro AraújoReis, Ana Luíza Marquesde Cássia dos Reis, MarcelaMazzola, Thamiresda Cruz Pegoraro, João VitorNeto, Sebastião Orestes Pereirade Lima, Daniela CoelhoD’Alpino, Paulo Henrique Perlatti [UNESP]2025-06-24T05:33:56Zoai:repositorio.unesp.br:11449/302285Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462025-06-24T05:33:56Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
title Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
spellingShingle Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
Fernandes, Leandro Araújo
Clinical trial
dentin hypersensitivity
desensitizing
toothpaste
title_short Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
title_full Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
title_fullStr Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
title_full_unstemmed Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
title_sort Bioactive silicon-based dental gel associated with a calcium booster for dentin hypersensitivity treatment: A randomized clinical study
dc.creator.none.fl_str_mv Fernandes, Leandro Araújo
Reis, Ana Luíza Marques
de Cássia dos Reis, Marcela
Mazzola, Thamires
da Cruz Pegoraro, João Vitor
Neto, Sebastião Orestes Pereira
de Lima, Daniela Coelho
D’Alpino, Paulo Henrique Perlatti [UNESP]
author Fernandes, Leandro Araújo
author_facet Fernandes, Leandro Araújo
Reis, Ana Luíza Marques
de Cássia dos Reis, Marcela
Mazzola, Thamires
da Cruz Pegoraro, João Vitor
Neto, Sebastião Orestes Pereira
de Lima, Daniela Coelho
D’Alpino, Paulo Henrique Perlatti [UNESP]
author_role author
author2 Reis, Ana Luíza Marques
de Cássia dos Reis, Marcela
Mazzola, Thamires
da Cruz Pegoraro, João Vitor
Neto, Sebastião Orestes Pereira
de Lima, Daniela Coelho
D’Alpino, Paulo Henrique Perlatti [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de Alfenas (UNIFALMG)
Inc.
Universidade Estadual Paulista (UNESP)
dc.subject.por.fl_str_mv Clinical trial
dentin hypersensitivity
desensitizing
toothpaste
topic Clinical trial
dentin hypersensitivity
desensitizing
toothpaste
description Background: Dentin hypersensitivity affects a significant portion of the world’s population, causing pain and negatively impacting oral health and quality of life This clinical study investigated the effectiveness of a desensitizing fluoride silicon-rich dental gel associated with a calcium booster. Material and Methods: In this single-blind, randomized, parallel-group clinical trial, forty-eight volunteers diagnosed with dentin hypersensitivity and qualified to participate were randomized into 2 groups: (1) fluoride silicon-rich dental gel (REFX Technology)/calcium booster (Si/Ca protocol); (2) Pumice stone diluted in saline. A draw was carried out between the right and left sides of the patients so that either a prophylaxis with the dental gel associated with calcium or with fine pumice stone diluted in saline was carried out. An evaporative test was used to check for dentin hypersensitivity in the subjects before and immediately after treatment and scored using the Schiff scale, rated 0 to 3. Data were statistically analyzed (ANOVA/Tukey test, α=5%). Results: The treatment with Si/Ca protocol drastically reduced dentin hypersensitivity (from 2.58 to 0.67) immediately after the use. In the control group (Pumice stone), similar results were observed before and after treatment (2.67 and 2.82, respectively). Conclusions: The Si/Ca protocol was fast and effective in reducing pain caused by dentin hypersensitivity.
publishDate 2024
dc.date.none.fl_str_mv 2024-01-01
2025-04-29T19:14:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4317/jced.62205
Journal of Clinical and Experimental Dentistry, v. 16, n. 12, p. e1475-e1480, 2024.
1989-5488
https://hdl.handle.net/11449/302285
10.4317/jced.62205
2-s2.0-85211142938
url http://dx.doi.org/10.4317/jced.62205
https://hdl.handle.net/11449/302285
identifier_str_mv Journal of Clinical and Experimental Dentistry, v. 16, n. 12, p. e1475-e1480, 2024.
1989-5488
10.4317/jced.62205
2-s2.0-85211142938
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Clinical and Experimental Dentistry
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv e1475-e1480
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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