ESTUDO COMPARATIVO ENTRE OS TESTES ADOTADOS PELO PNCEBT PARA O DIAGNÓSTICO SOROLÓGICO DA BRUCELOSE EM BOVINOS*

Serum samples from 1,061 bovine were analyzed by serological diagnostic techniques adopted by the Brazilian Program for Animal Brucellosis and Tuberculosis Control and Eradication in order to compare, as a screening test, the rose Bengal plate test (RBPT), and as confirmatory tests, the 2-mercaptoet...

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Detalles Bibliográficos
Autores: Meirelles-bartoli, R.b. [UNESP], Mathias, L.a. [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:portugués
OAI Identifier:oai:repositorio.unesp.br:11449/211985
Acceso en línea:http://dx.doi.org/10.1590/1808-1657v77p0112010
http://hdl.handle.net/11449/211985
Access Level:acceso abierto
Palabra clave:Bovine brucellosis
serodiagnosis
agreement
sensitivity
specificity
Brucelose bovina
diagnóstico sorológico
concordância
sensibilidade diagnóstica
especificidade diagnóstica
Descripción
Sumario:Serum samples from 1,061 bovine were analyzed by serological diagnostic techniques adopted by the Brazilian Program for Animal Brucellosis and Tuberculosis Control and Eradication in order to compare, as a screening test, the rose Bengal plate test (RBPT), and as confirmatory tests, the 2-mercaptoethanol plus standard tube agglutination test (2-ME), and the complement fixation test (CFT). Relative sensitivity of 99.6%, 98.8% and 91.1% were observed, respectively, for RBPT, 2-ME and CFT, and relative specificity of 83.9%, 96.2% and 100.0%. The agreement between tests was analyzed by the kappa statistic (2-ME cut-off = titer 25, and CFT cutoff = titer 4). RBPT showed a substantial agreement (kappa: 2-ME = 0.80; and RFC = 0.73) with the confirmatory tests, and excellent agreement between the confirmatory tests (kappa = 0.86) was observed. However sera with a negative result in one of the confirmatory tests and a high titer in the other were observed, reinforcing that the serological diagnosis of bovine brucellosis is more reliable when based on the results of several tests.