Occurrence and composition of class 1 and class 2 integrons in clinical and environmental O1 and non-O1/non-O139 Vibrio cholerae strains from the Brazilian Amazon
This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2010 |
| País: | Brasil |
| Institución: | Instituto Evandro Chagas (IEC) |
| Repositorio: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
| Idioma: | inglés |
| OAI Identifier: | oai:patua.iec.gov.br:iec/476 |
| Acceso en línea: | https://patua.iec.gov.br/handle/iec/476 |
| Access Level: | acceso abierto |
| Palabra clave: | Vibrio cholerae / isolamento & purificação Vibrio cholerae / classificação Reação em Cadeia da Polimerase Ecossistema Amazônico Região Amazônica (BR) |
| Sumario: | This study identified and characterised class 1 and 2 integrons in clinical and environmental Vibrio cholerae O1 and non-O1/non-O139 strains isolated from the Brazilian Amazon. The aadA2 and aadA7 gene cassettes were found in class 1 integrons in two genotypes of environmental V. cholerae non-O1/non-O139. Empty integrons were found in strains from the Brazilian cholera epidemic. A class 2 integron was detected in one strain from the V. cholerae Amazonia lineage harbouring sat1 and aadA1 genes. All isolates were resistant to aminoglycosides, indicating aadA functionality. These findings suggest that environmental bacteria act as cassette reservoirs that favour the emergence of resistant pathogens. |
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