Feohifomicose subcutânea por Exophiala jeanselmei em um transplantado cardíaco

We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers...

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Detalles Bibliográficos
Autores: Silva, Maria do Rosário R., Fernandes, Orionalda de F.L., Costa, Carolina R., Chaul, Aiçar, Morgado, Luciano F., Fleury-Júnior, Luis Fernando, Costa, Maurício B.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2005
País:Brasil
Institución:Instituto de Medicina Tropical (IMT)
Repositorio:Revista do Instituto de Medicina Tropical de São Paulo
Idioma:inglés
OAI Identifier:oai:revistas.usp.br:article/30884
Acceso en línea:https://www.revistas.usp.br/rimtsp/article/view/30884
Access Level:acceso abierto
Palabra clave:Exophiala jeanselmei
Phaeohyphomycosis
Subcutaneous infections
Descripción
Sumario:We report a case of phaeohyphomycosis caused by Exophiala jeanselmei in a cardiac transplant recipient maintained on immunosuppressive therapy with mycophenolate mofetil tacrolimus and prednisone. The lesion began after trauma on the right leg that evolved to multiple lesions with nodules and ulcers. Diagnosis was performed by histological examination and culture of pus from skin lesions. Treatment consisted of itraconazole (200 mg/day) for three months with no improvement and subsequently with amphotericin B (0.5 mg/Kg per day to a total of 3.8 g intravenously). After four months of treatment, the lesions showed marked improvement with reduction in the swelling and healing of sinuses and residual scaring.