Non-enzymatic impedimetric sensor based on 3-aminophenylboronic acid functionalized screen-printed carbon electrode for highly sensitive glucose detection
A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to...
| Authors: | , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2019 |
| Country: | Brasil |
| Institution: | Universidade Federal de Minas Gerais (UFMG) |
| Repository: | Repositório Institucional da UFMG |
| Language: | English |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/57518 |
| Online Access: | https://doi.org/10.3390/s19071686 http://hdl.handle.net/1843/57518 https://orcid.org/0000-0002-7025-7042 https://orcid.org/0000-0003-0707-2691 https://orcid.org/0000-0002-5660-8125 https://orcid.org/0000-0002-0868-2726 |
| Access Level: | Open access |
| Keyword: | Sensor Glucose Electrochemical impedance spectroscopy Boronic acid Eletroquímica Detectores eletroquímicos Espectroscopia de impedância Glicose |
| Summary: | A highly sensitive glucose sensor was prepared by a one-step method using 3-aminophenyl boronic acid as a unit of recognition and a screen-printed carbon electrode (SPCE) as an electrochemical transducer. Scanning Electron Microscopy confirmed the success of the functionalization of the SPCE due to the presence of clusters of boronic acid distributed on the carbon surface. In agreement with the Electrochemical Impedance Spectroscopy (EIS) tests performed before and after the functionalization, Cyclic Voltammetry results indicated that the electroactivity of the electrode decreased 37.9% owing to the presence of the poly phenylboronic acid on the electrode surface. EIS revealed that the sensor was capable to selectively detect glucose at a broad range of concentrations (limit of detection of 8.53 × 10−9 M), not recognizing fructose and sucrose. The device presented a stable impedimetric response when immediately prepared but suffered the influence of the storage time and some interfering species (dopamine, NaCl and animal serum). The response time at optimized conditions was estimated to be equal to 4.0 ± 0.6 s. |
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