Prevalence of coronary artery disease in simultaneous pancreas-kidney transplantation candidates

Purpose: The purpose of the study was to assess the prevalence and degree of coronary artery disease (CAD) in asymptomatic simultaneous pancreas-kidney (SPK) transplantation candidates in a Southern Brazilian transplant center. Methods: This retrospective study included 40 SPK transplantation candid...

ver descrição completa

Detalhes bibliográficos
Autores: Coelho, Juliano Cé, Siqueira, Rodrigo Morais de, Farret, Túlio Cícero Franco, Fritsch, Mariane, Fedrizzi, Renata, Goldbaum Jr, Maurício, Kroth, Leonardo V., Hartmann, Marcelo, Falavigna, Manlio, Traessel, Moacir Alexandre, d’Avila, Domingos, Gullo Neto, Salvador, Saitovitch, David
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2007
País:Brasil
Recursos:Associação Brasileira de Transplante de Órgãos (ABTO)
Repositorio:Brazilian Journal of Transplantation
Idioma:portugués
OAI Identifier:oai:ojs3.emnuvens.com.br:article/346
Acesso em linha:https://bjt.emnuvens.com.br/revista/article/view/346
Access Level:acceso abierto
Palavra-chave:Diabete Mellitus
Insuficiência Renal Crônica
Transplante de Rim
Transplante de Pâncreas
Coronariopatia
Prevalência
Diabetes Mellitus
Chronic Renal Insufficiency
Kidney Transplantation
Pancreas Transplantation
Coronary Disease
Prevalence
Descrição
Resumo:Purpose: The purpose of the study was to assess the prevalence and degree of coronary artery disease (CAD) in asymptomatic simultaneous pancreas-kidney (SPK) transplantation candidates in a Southern Brazilian transplant center. Methods: This retrospective study included 40 SPK transplantation candidates, enrolled on the transplant waiting list between May 2002 and May 2007, with type 1 Diabetes Mellitus (DM1) and Chronic Renal Failure (CRF). They were divided in two groups according to the coronary angiography: group I, patients with CAD, and group II, patients without CAD. The severity of the coronary illness was also assessed. Results: 52.5% were men and the mean age was 35.7± 9.01 years-old. The prevalence of coronary artery disease in simultaneous pancreas-kidney transplantation candidates was 40%, and 81.25% of them presented severe injury. Conclusions: Asymptomatic patients enrolled in the transplant waiting list for SPK presented a high prevalence of CAD. No independent risk factors for the CAD development have been found in the present analysis.