Aspectos histológicos de fragmentos esplênicos autotransplantados em ratos
The splenic tissue autograft viability (one third of the spleen) associated to parcial splenectomy was studied to verify the evolutive kinetic of its regeneration by macroscopic and histological aspects. Twenty-eight adult male Wistar rats, weighting 300g, were distributed in four experimental group...
| Authors: | , , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2010 |
| Country: | Brasil |
| Institution: | Universidade Federal de São Paulo (UNIFESP) |
| Repository: | Repositório Institucional da UNIFESP |
| Language: | Portuguese |
| OAI Identifier: | oai:repositorio.unifesp.br:11600/5761 |
| Online Access: | http://dx.doi.org/10.1590/S0102-09352010000300020 http://repositorio.unifesp.br/handle/11600/5761 |
| Access Level: | Open access |
| Keyword: | rat splenic regeneration spleen rato regeneração esplênica baço |
| Summary: | The splenic tissue autograft viability (one third of the spleen) associated to parcial splenectomy was studied to verify the evolutive kinetic of its regeneration by macroscopic and histological aspects. Twenty-eight adult male Wistar rats, weighting 300g, were distributed in four experimental groups. Each animal was submitted to parcial splenectomy and one fragment of each spleen was autotransplanted to the greater omentum, for a period of 30, 60, 90, and 120 days. After each period, the autotransplanted splenic tissues were collected and histopathologically analyzed. The results showed regeneration of the splenic capsule, blood vessels, white pulp, and red pulp. After 90 days, the microscopic architecture was similar to the normal spleen. |
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