Diagnóstico del Helicobacter pylori: comparación entre la prueba de urease, examen histológico de bacterias curvas y el cultivo

Helicobacter pylori was investigated in 189 patients for culture, microscopic visualization of campylobacter-like organisms (CLO) and a ten minute urease test. In 136 (72%) the bacteria was isolated, and in 98 of them CLO were histologically detected. Specificity, sensitivity, positive and negative...

Full description

Bibliographic Details
Authors: Hernández, Francisco, Rivera, Patrícia, Sigarán, Manuel, Miranda, Jorge
Format: article
Status:Published version
Publication Date:1991
Country:Brasil
Institution:Instituto de Medicina Tropical (IMT)
Repository:Revista do Instituto de Medicina Tropical de São Paulo
Language:English
OAI Identifier:oai:revistas.usp.br:article/28797
Online Access:https://www.revistas.usp.br/rimtsp/article/view/28797
Access Level:Open access
Keyword:Campylobacter pylori
Helicobacter pylori
Diagnostic
Technical assay
Campylobacter-like organisms
Urease test
Description
Summary:Helicobacter pylori was investigated in 189 patients for culture, microscopic visualization of campylobacter-like organisms (CLO) and a ten minute urease test. In 136 (72%) the bacteria was isolated, and in 98 of them CLO were histologically detected. Specificity, sensitivity, positive and negative predictive values of microscopic visualization of CLO were: 0.77, 0.73, 0.97 and 0.51, respectively; 98 culture-positive patients were urease test positive. Specificity, sensitivity, positive and negative predictive values of the urease test were: 0.83, 0.72, 0.92 and 0.54, respectively. Comparing the urease test with culture of H. pylori combined with microscopic visualization of CLO, its specificity, sensitivity, positive and negative predictive values were: 0.95, 0.71, 0.98 and 0.48, respectively. Probably, these values are not real, since bacteria different from H. pylori could be misclassified as CLO.