Protein interactions with osseointegrable titanium implants
This review aims to present the mechanisms of protein interactions with titanium dental implant surfaces. Methods: the analyses were based on searches of scientific articles available in English and Portuguese in PubMed (MEDLINE), Bireme (LILACS), Scielo, Web of Science and Google Scholar. Results:...
| Autores: | , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2023 |
| País: | Brasil |
| Institución: | Universidade Estadual de Campinas (UNICAMP) |
| Repositorio: | Brazilian journal of oral sciences (Online) |
| Idioma: | inglés |
| OAI Identifier: | oai:ojs.periodicos.sbu.unicamp.br:article/8668749 |
| Acceso en línea: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8668749 |
| Access Level: | acceso abierto |
| Palabra clave: | Osseointegration Bone-implant inteface Dental implants Proteins |
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Protein interactions with osseointegrable titanium implantsOsseointegrationBone-implant intefaceDental implantsProteinsThis review aims to present the mechanisms of protein interactions with titanium dental implant surfaces. Methods: the analyses were based on searches of scientific articles available in English and Portuguese in PubMed (MEDLINE), Bireme (LILACS), Scielo, Web of Science and Google Scholar. Results: titanium dental implant treatments success rates (95-98%) are mainly due to the biocompatibility of titanium oxide on the implant surface, surgical techniques adopted, good implants manufacturing processes and biomechanical knowledge of the systems. Studies in past decades has empirically developed implant surfaces with significant changes in morphologies, roughness, wettability, surface energy, chemical composition, and chemical groups density or deposited molecules. These changes promoted better protein adsorption, osteoblast adhesion, and changes in the mechanisms involved in osseointegration. Thus, the time to put the implant in function has been reduced and the success rates have increased. In the osseointegration process, at the nanoscale, there is no contact between the bone and the implant surface, but there is the formation of a protein anchorage between the periosteum and the implant with an interface formed by proteins. In all the reactions between the body and the implant surface, the activities of fibronectin and integrin are essential, since they are responsible for transmitting information to the cell for its differentiation, adhesion and mobility. Conclusion: thus, the analyses of protein-implant interactions are indispensable for a better understanding of the performance of osseointegrated dental implants.Universidade Estadual de Campinas2023-10-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/866874910.20396/bjos.v22i00.8668749Brazilian Journal of Oral Sciences; v. 22 (2023): Continuous Publication; e238749Brazilian Journal of Oral Sciences; Vol. 22 (2023): Continuous Publication; e2387491677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8668749/32612Brazil; ContemporanyCopyright (c) 2022 Marvin do Nascimento, Thays Obando Brito, Andreza Menezes Lima, Carlos Nelson Eliashttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessNascimento, Marvin doBrito, Thays ObandoLima, Andreza MenezesElias, Carlos Nelson2023-10-17T12:13:19Zoai:ojs.periodicos.sbu.unicamp.br:article/8668749Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2023-10-17T12:13:19Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false |
| dc.title.none.fl_str_mv |
Protein interactions with osseointegrable titanium implants |
| title |
Protein interactions with osseointegrable titanium implants |
| spellingShingle |
Protein interactions with osseointegrable titanium implants Nascimento, Marvin do Osseointegration Bone-implant inteface Dental implants Proteins |
| title_short |
Protein interactions with osseointegrable titanium implants |
| title_full |
Protein interactions with osseointegrable titanium implants |
| title_fullStr |
Protein interactions with osseointegrable titanium implants |
| title_full_unstemmed |
Protein interactions with osseointegrable titanium implants |
| title_sort |
Protein interactions with osseointegrable titanium implants |
| dc.creator.none.fl_str_mv |
Nascimento, Marvin do Brito, Thays Obando Lima, Andreza Menezes Elias, Carlos Nelson |
| author |
Nascimento, Marvin do |
| author_facet |
Nascimento, Marvin do Brito, Thays Obando Lima, Andreza Menezes Elias, Carlos Nelson |
| author_role |
author |
| author2 |
Brito, Thays Obando Lima, Andreza Menezes Elias, Carlos Nelson |
| author2_role |
author author author |
| dc.subject.por.fl_str_mv |
Osseointegration Bone-implant inteface Dental implants Proteins |
| topic |
Osseointegration Bone-implant inteface Dental implants Proteins |
| description |
This review aims to present the mechanisms of protein interactions with titanium dental implant surfaces. Methods: the analyses were based on searches of scientific articles available in English and Portuguese in PubMed (MEDLINE), Bireme (LILACS), Scielo, Web of Science and Google Scholar. Results: titanium dental implant treatments success rates (95-98%) are mainly due to the biocompatibility of titanium oxide on the implant surface, surgical techniques adopted, good implants manufacturing processes and biomechanical knowledge of the systems. Studies in past decades has empirically developed implant surfaces with significant changes in morphologies, roughness, wettability, surface energy, chemical composition, and chemical groups density or deposited molecules. These changes promoted better protein adsorption, osteoblast adhesion, and changes in the mechanisms involved in osseointegration. Thus, the time to put the implant in function has been reduced and the success rates have increased. In the osseointegration process, at the nanoscale, there is no contact between the bone and the implant surface, but there is the formation of a protein anchorage between the periosteum and the implant with an interface formed by proteins. In all the reactions between the body and the implant surface, the activities of fibronectin and integrin are essential, since they are responsible for transmitting information to the cell for its differentiation, adhesion and mobility. Conclusion: thus, the analyses of protein-implant interactions are indispensable for a better understanding of the performance of osseointegrated dental implants. |
| publishDate |
2023 |
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2023-10-16 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/other |
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article |
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publishedVersion |
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https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8668749 10.20396/bjos.v22i00.8668749 |
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https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8668749 |
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10.20396/bjos.v22i00.8668749 |
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eng |
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eng |
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https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8668749/32612 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Brazil; Contemporany |
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Universidade Estadual de Campinas |
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Universidade Estadual de Campinas |
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Brazilian Journal of Oral Sciences; v. 22 (2023): Continuous Publication; e238749 Brazilian Journal of Oral Sciences; Vol. 22 (2023): Continuous Publication; e238749 1677-3225 reponame:Brazilian journal of oral sciences (Online) instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
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Universidade Estadual de Campinas (UNICAMP) |
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UNICAMP |
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UNICAMP |
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Brazilian journal of oral sciences (Online) |
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Brazilian journal of oral sciences (Online) |
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Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP) |
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brjorals@fop.unicamp.br||brjorals@fop.unicamp.br |
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