Primary lacrimal gland sebaceous carcinoma–case presentation and literature review

Primary sebaceous carcinoma of the lacrimal gland (PSCLG) is the rarest lacrimal gland (LG) tumor, often belatedly diagnosed, worsening the prognosis. We present a 68-year-old man with a large, indurated mass in the left orbital outer quadrant, visible at the conjunctival upper temporal fornix, exte...

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Detalles Bibliográficos
Autores: Schellini, Silvana A. [UNESP], Santos Souza, Daniela [UNESP], Almeida, Amanda A. M. P. [UNESP], Schellini, Rodolfo A. [UNESP], Ferraz, Lucieni C. B.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/303790
Acceso en línea:http://dx.doi.org/10.1080/01676830.2023.2291059
https://hdl.handle.net/11449/303790
Access Level:acceso abierto
Palabra clave:case report
lacrimal gland
literature revision
Primary sebaceous carcinoma
Descripción
Sumario:Primary sebaceous carcinoma of the lacrimal gland (PSCLG) is the rarest lacrimal gland (LG) tumor, often belatedly diagnosed, worsening the prognosis. We present a 68-year-old man with a large, indurated mass in the left orbital outer quadrant, visible at the conjunctival upper temporal fornix, extending to the lower fornix, with left gaze restriction. The lesion was not related to the eyelid or other periocular tissues. Excisional biopsy revealed the PSCLG diagnosis. There are only eight others previous PSCLGs. Males are the most affected. Indurated mass in the lacrimal fossa, with eyelid in “S” shape is the most common presentation. Image exams are suggestive, but histological and immunohistochemical evaluations showing a single tumor cell line within LG are mandatory for definitive diagnosis. Larger and more extensive lesions can have a poor prognosis, but early detection can favor the outcome.