Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology

The study of cigarette authenticity in Brazil is important due to increasing consumption of contraband cigarettes. Nicotine concentration is an important parameter reflecting the quality of tobacco used in the production of these cigarettes. Simple methods for this determination, which produce reduc...

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Autores: Domingues, Cinthia Eloise, Kordiak, Januário, Pedroso, Carlos R., Stremel, Tatiana R. de Oliveira, Zittel, Rosimara, Los Weinert, Patrícia, Vidal, Carlos M. de Sousa, de Campos, Sandro X.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Institución:Universidade Federal de Mato Grosso do Sul (UFMS)
Repositorio:Orbital - The Electronic Journal of Chemistry (Campo Grande)
Idioma:inglés
OAI Identifier:oai:periodicos.ufms.br:article/16188
Acceso en línea:https://periodicos.ufms.br/index.php/orbital/article/view/16188
Access Level:acceso abierto
Palabra clave:Doehlert matrix
Nicotine
QuEChERS
Smuggled cigarettes
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spelling Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS MethodologyDoehlert matrixNicotineQuEChERSSmuggled cigarettesThe study of cigarette authenticity in Brazil is important due to increasing consumption of contraband cigarettes. Nicotine concentration is an important parameter reflecting the quality of tobacco used in the production of these cigarettes. Simple methods for this determination, which produce reduced waste, are environmentally and industrially important. The nicotine concentration of smuggled cigarette tobacco was determined by the QuEChERS method, requiring some modifications, such as decreasing the volume of the extractor solvent, changes in pH, and removal of the sample hydration step. Quantification was performed by gas chromatography using a flame ionization detector. The Doehlert matrix design was used to optimize the method. The extraction recoveries ranged from 97.5% to 99.6%, with relative standard deviation (RSD) ≤ 2.5% and limits of detection and quantification of 0.6 mg L-1 and 2.5 mg L-1, respectively. The method was sensitive and accurate for the detection and quantification of nicotine. The nicotine concentration in contraband cigarettes was found to be lower than that observed in legal cigarettes. The method was successfully applied to real samples of smuggled and legal cigarettes, providing a robust method for routine analysis and proving the need for more studies on quality control of smuggled cigarettes in Brazil.Instituto de Química, Universidade Federal de Mato Grosso do Sul2022-07-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Articleapplication/pdfhttps://periodicos.ufms.br/index.php/orbital/article/view/1618810.17807/orbital.v14i2.16188Orbital: The Electronic Journal of Chemistry; Orbital - Vol. 14 No. 2 - April-June 2022; 68-73Orbital: The Electronic Journal of Chemistry; Orbital - Vol. 14 No. 2 - April-June 2022; 68-731984-6428reponame:Orbital - The Electronic Journal of Chemistry (Campo Grande)instname:Universidade Federal de Mato Grosso do Sul (UFMS)instacron:UFMSenghttps://periodicos.ufms.br/index.php/orbital/article/view/16188/10997Copyright (c) 2022 Orbital: The Electronic Journal of Chemistryhttps://creativecommons.org/licenses/by-nc-nd/4.0info:eu-repo/semantics/openAccessDomingues, Cinthia EloiseKordiak, JanuárioPedroso, Carlos R.Stremel, Tatiana R. de OliveiraZittel, RosimaraLos Weinert, PatríciaVidal, Carlos M. de Sousade Campos, Sandro X.2023-01-20T10:47:39Zoai:periodicos.ufms.br:article/16188Revistahttps://periodicos.ufms.br/index.php/orbital/indexPUBhttps://periodicos.ufms.br/index.php/orbital/oaieditor.orbital@ufms.br || marcos.amaral@ufms.br1984-64281984-6428opendoar:2023-01-20T10:47:39Orbital - The Electronic Journal of Chemistry (Campo Grande) - Universidade Federal de Mato Grosso do Sul (UFMS)false
dc.title.none.fl_str_mv Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
title Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
spellingShingle Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
Domingues, Cinthia Eloise
Doehlert matrix
Nicotine
QuEChERS
Smuggled cigarettes
title_short Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
title_full Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
title_fullStr Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
title_full_unstemmed Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
title_sort Determination of Nicotine in Cigarette Tobacco Smuggled to Brazil by Modified QuEChERS Methodology
dc.creator.none.fl_str_mv Domingues, Cinthia Eloise
Kordiak, Januário
Pedroso, Carlos R.
Stremel, Tatiana R. de Oliveira
Zittel, Rosimara
Los Weinert, Patrícia
Vidal, Carlos M. de Sousa
de Campos, Sandro X.
author Domingues, Cinthia Eloise
author_facet Domingues, Cinthia Eloise
Kordiak, Januário
Pedroso, Carlos R.
Stremel, Tatiana R. de Oliveira
Zittel, Rosimara
Los Weinert, Patrícia
Vidal, Carlos M. de Sousa
de Campos, Sandro X.
author_role author
author2 Kordiak, Januário
Pedroso, Carlos R.
Stremel, Tatiana R. de Oliveira
Zittel, Rosimara
Los Weinert, Patrícia
Vidal, Carlos M. de Sousa
de Campos, Sandro X.
author2_role author
author
author
author
author
author
author
dc.subject.por.fl_str_mv Doehlert matrix
Nicotine
QuEChERS
Smuggled cigarettes
topic Doehlert matrix
Nicotine
QuEChERS
Smuggled cigarettes
description The study of cigarette authenticity in Brazil is important due to increasing consumption of contraband cigarettes. Nicotine concentration is an important parameter reflecting the quality of tobacco used in the production of these cigarettes. Simple methods for this determination, which produce reduced waste, are environmentally and industrially important. The nicotine concentration of smuggled cigarette tobacco was determined by the QuEChERS method, requiring some modifications, such as decreasing the volume of the extractor solvent, changes in pH, and removal of the sample hydration step. Quantification was performed by gas chromatography using a flame ionization detector. The Doehlert matrix design was used to optimize the method. The extraction recoveries ranged from 97.5% to 99.6%, with relative standard deviation (RSD) ≤ 2.5% and limits of detection and quantification of 0.6 mg L-1 and 2.5 mg L-1, respectively. The method was sensitive and accurate for the detection and quantification of nicotine. The nicotine concentration in contraband cigarettes was found to be lower than that observed in legal cigarettes. The method was successfully applied to real samples of smuggled and legal cigarettes, providing a robust method for routine analysis and proving the need for more studies on quality control of smuggled cigarettes in Brazil.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.ufms.br/index.php/orbital/article/view/16188
10.17807/orbital.v14i2.16188
url https://periodicos.ufms.br/index.php/orbital/article/view/16188
identifier_str_mv 10.17807/orbital.v14i2.16188
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.ufms.br/index.php/orbital/article/view/16188/10997
dc.rights.driver.fl_str_mv Copyright (c) 2022 Orbital: The Electronic Journal of Chemistry
https://creativecommons.org/licenses/by-nc-nd/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Orbital: The Electronic Journal of Chemistry
https://creativecommons.org/licenses/by-nc-nd/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Instituto de Química, Universidade Federal de Mato Grosso do Sul
publisher.none.fl_str_mv Instituto de Química, Universidade Federal de Mato Grosso do Sul
dc.source.none.fl_str_mv Orbital: The Electronic Journal of Chemistry; Orbital - Vol. 14 No. 2 - April-June 2022; 68-73
Orbital: The Electronic Journal of Chemistry; Orbital - Vol. 14 No. 2 - April-June 2022; 68-73
1984-6428
reponame:Orbital - The Electronic Journal of Chemistry (Campo Grande)
instname:Universidade Federal de Mato Grosso do Sul (UFMS)
instacron:UFMS
instname_str Universidade Federal de Mato Grosso do Sul (UFMS)
instacron_str UFMS
institution UFMS
reponame_str Orbital - The Electronic Journal of Chemistry (Campo Grande)
collection Orbital - The Electronic Journal of Chemistry (Campo Grande)
repository.name.fl_str_mv Orbital - The Electronic Journal of Chemistry (Campo Grande) - Universidade Federal de Mato Grosso do Sul (UFMS)
repository.mail.fl_str_mv editor.orbital@ufms.br || marcos.amaral@ufms.br
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score 15,301603