Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?

Objective: Rapid Eye Movement Sleep Deprivation (RSD) increases aggressiveness and is manifested in male rats as fighting episodes. The determination of the role played by such fights should constitute an important contribution toward assessing the adaptive function of this type of sleep. Neverthele...

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Authors: Molico, Eveline [UNESP], Hoshino, Katsumasa [UNESP]
Format: article
Status:Published version
Publication Date:2010
Country:Brasil
Institution:Universidade Estadual Paulista (UNESP)
Repository:Repositório Institucional da UNESP
Language:English
Portuguese
OAI Identifier:oai:repositorio.unesp.br:11449/227512
Online Access:http://hdl.handle.net/11449/227512
Access Level:Open access
Keyword:Aggression
Panic/physiology
Physiology
Rats
REM
Sleep
Sleep deprivation/physiopathology
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spelling Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?Prevalence of flight response in female rats: Does it explain the reported gender difference in sleep deprivation related aggressiveness?AggressionPanic/physiologyPhysiologyRatsREMSleepSleep deprivation/physiopathologyObjective: Rapid Eye Movement Sleep Deprivation (RSD) increases aggressiveness and is manifested in male rats as fighting episodes. The determination of the role played by such fights should constitute an important contribution toward assessing the adaptive function of this type of sleep. Nevertheless, female rats do not exhibit such behavior. Recent data indicate that RSD-induced fighting and wild running flights are panic manifestations, thus advancing the hypothesis that female rats do not fight because their prevalent response in panic situations is flight. Methods: Therefore, 10 male and 12 female rats were acoustically kindled at 14 days of age, and their susceptibility to display wild running was evaluated at 30, 60 and 90 days of age. Results: 6 males and 10 females produced respective totals of 12 and 30 wild running episodes (chi-square test, p=0.0003), with mean (± standard error) of 0.60±0.21 and 1.41±0.24 episodes/rat. (ANOVA/MANOVA, p=0.0169). Conclusions: The results validate the hypothesis and are concordant with the higher frequency of panic attacks observed in women as compared to men.Department of Biological Sciences Universidade Estadual Paulista 'Júlio de Mesquita Filho' - UNESP, Bauru (SP)Department of Biological Sciences Universidade Estadual Paulista 'Júlio de Mesquita Filho' - UNESP, Bauru (SP)Universidade Estadual Paulista (UNESP)2022-04-29T07:13:43Z2022-04-29T07:13:43Z2010-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article95-98Sleep Science, v. 3, n. 3, p. 95-98, 2010.1984-06591984-0063http://hdl.handle.net/11449/2275122-s2.0-84893007680Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporSleep Scienceinfo:eu-repo/semantics/openAccessMolico, Eveline [UNESP]Hoshino, Katsumasa [UNESP]2025-06-24T05:04:54Zoai:repositorio.unesp.br:11449/227512Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462025-06-24T05:04:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
Prevalence of flight response in female rats: Does it explain the reported gender difference in sleep deprivation related aggressiveness?
title Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
spellingShingle Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
Molico, Eveline [UNESP]
Aggression
Panic/physiology
Physiology
Rats
REM
Sleep
Sleep deprivation/physiopathology
title_short Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
title_full Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
title_fullStr Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
title_full_unstemmed Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
title_sort Prevalência da resposta de fuga em ratas: Isto explica a diferença de gênero na agressividade da privação de sono?
dc.creator.none.fl_str_mv Molico, Eveline [UNESP]
Hoshino, Katsumasa [UNESP]
author Molico, Eveline [UNESP]
author_facet Molico, Eveline [UNESP]
Hoshino, Katsumasa [UNESP]
author_role author
author2 Hoshino, Katsumasa [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.subject.por.fl_str_mv Aggression
Panic/physiology
Physiology
Rats
REM
Sleep
Sleep deprivation/physiopathology
topic Aggression
Panic/physiology
Physiology
Rats
REM
Sleep
Sleep deprivation/physiopathology
description Objective: Rapid Eye Movement Sleep Deprivation (RSD) increases aggressiveness and is manifested in male rats as fighting episodes. The determination of the role played by such fights should constitute an important contribution toward assessing the adaptive function of this type of sleep. Nevertheless, female rats do not exhibit such behavior. Recent data indicate that RSD-induced fighting and wild running flights are panic manifestations, thus advancing the hypothesis that female rats do not fight because their prevalent response in panic situations is flight. Methods: Therefore, 10 male and 12 female rats were acoustically kindled at 14 days of age, and their susceptibility to display wild running was evaluated at 30, 60 and 90 days of age. Results: 6 males and 10 females produced respective totals of 12 and 30 wild running episodes (chi-square test, p=0.0003), with mean (± standard error) of 0.60±0.21 and 1.41±0.24 episodes/rat. (ANOVA/MANOVA, p=0.0169). Conclusions: The results validate the hypothesis and are concordant with the higher frequency of panic attacks observed in women as compared to men.
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
2022-04-29T07:13:43Z
2022-04-29T07:13:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Sleep Science, v. 3, n. 3, p. 95-98, 2010.
1984-0659
1984-0063
http://hdl.handle.net/11449/227512
2-s2.0-84893007680
identifier_str_mv Sleep Science, v. 3, n. 3, p. 95-98, 2010.
1984-0659
1984-0063
2-s2.0-84893007680
url http://hdl.handle.net/11449/227512
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv Sleep Science
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 95-98
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
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score 15,301603

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