Effect of Zingiber officinale and propolis on microorganisms and endotoxins in root canals
The purpose of this study was to evaluate the effectiveness of glycolic propolis (PRO) and ginger (GIN) extracts, calcium hydroxide (CH), chlorhexidine (CLX) gel and their combinations as ICMs (ICMs) against Candida albicans, Enterococcus faecalis, Escherichia coli and endotoxins in root canals. Mat...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2013 |
| País: | Brasil |
| Institución: | Universidade Estadual Paulista (UNESP) |
| Repositorio: | Repositório Institucional da UNESP |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.unesp.br:11449/75900 |
| Acceso en línea: | http://dx.doi.org/10.1590/1678-7757201302129 http://hdl.handle.net/11449/75900 |
| Access Level: | acceso abierto |
| Palabra clave: | Calcium hydroxide Candida albicans Enterococcus faecalis Escherichia coli. endotoxins Propolis Zingiber officinale biomedical and dental materials calcium hydroxide chlorhexidine disinfectant agent endotoxin propolis chemistry drug effect endodontics Escherichia coli ginger human microbiology nonparametric test time tooth pulp Calcium Hydroxide Chlorhexidine Dental Pulp Cavity Disinfectants Endotoxins Ginger Humans Root Canal Irrigants Root Canal Preparation Statistics, Nonparametric Time Factors |
| Sumario: | The purpose of this study was to evaluate the effectiveness of glycolic propolis (PRO) and ginger (GIN) extracts, calcium hydroxide (CH), chlorhexidine (CLX) gel and their combinations as ICMs (ICMs) against Candida albicans, Enterococcus faecalis, Escherichia coli and endotoxins in root canals. Material and Methods: After 28 days of contamination with microorganisms, the canals were instrumented and then divided according to the ICM: CH+saline; CLX, CH+CLX, PRO, PRO+CH; GIN; GIN+CH; saline. The antimicrobial activity and quantification of endotoxins by the chromogenic test of Limulus amebocyte lysate were evaluated after contamination and instrumentation at 14 days of ICM application and 7 days after ICM removal. Results and Conclusion: After analysis of results and application ofthe Kruskal-Wallis and Dunn statistical tests at 5% significance level, it was concluded that all ICMs were able to eliminate the microorganisms in the root canals and reduce their amount of endotoxins; however, CH was more effective in neutralizing endotoxins and less effective against C. albicans and E. faecalis, requiring the use of medication combinations to obtain higher success. |
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