Gas chromatography analysis of amphetamines and benzodiazepines in formulas for slim. Study I: determination of diethylpropion and femproporex
This present study describes a gas chromatography method for simultaneous determination of diethylpropion and fenproporex that are present in formulas indicated for weight loosing diets. This method was applied in three different formulas, consisting of drugs, in a range of quantities most commonly...
| Autores: | , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 1999 |
| País: | Brasil |
| Recursos: | Instituto Adolfo Lutz |
| Repositorio: | Revista do Instituto Adolfo Lutz (Online) |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.periodicos.saude.sp.gov.br:article/36681 |
| Acesso em linha: | https://periodicos.saude.sp.gov.br/RIAL/article/view/36681 |
| Access Level: | acceso abierto |
| Palavra-chave: | Gas chromatography diethylpropion fenproporex formulas for slim Cromatografia gasosa dietilpropiona femproporex formulações para regime de emagrecimento |
| Resumo: | This present study describes a gas chromatography method for simultaneous determination of diethylpropion and fenproporex that are present in formulas indicated for weight loosing diets. This method was applied in three different formulas, consisting of drugs, in a range of quantities most commonly prescribed. The method consisted of amphetamines extraction with methylene chloride, followed by gas chromatography analysis, using phenylpropanolamine as an internal standard. The separation between the two substances was observed, with a retention time of 3,7 minutes for diethylpropion and 4,3 minutes for fenproporex. The maximum variation coefficient for the diethylpropion method was 2,28% and for the fenproporex it was 2,41 %. |
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