Effects of the solubility of yeast cell wall preparations on their potential prebiotic properties in dogs
Derivatives of yeast cell wall (YCW) have been studied for their potential prebiotic effects. Recently, new purified and solublepreparations have been developed in an attempt to increase their biological actions. Two YCW preparations, one conventional andanother with higher solubility of the mannan...
| Autores: | , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2019 |
| País: | Brasil |
| Recursos: | Universidade Federal de Minas Gerais (UFMG) |
| Repositorio: | Repositório Institucional da UFMG |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/40865 |
| Acesso em linha: | http://hdl.handle.net/1843/40865 |
| Access Level: | acceso abierto |
| Palavra-chave: | Cell wall preparations Potential prebiotic Dogs Ciência e Tecnologia de Alimentos Medicina Veterinária Cachorros |
| Resumo: | Derivatives of yeast cell wall (YCW) have been studied for their potential prebiotic effects. Recently, new purified and solublepreparations have been developed in an attempt to increase their biological actions. Two YCW preparations, one conventional andanother with higher solubility of the mannan oligosaccharide fraction, were evaluated on dogs. One food formulation was used,divided into the following treatments: CON–control, without yeast cell wall addition; YCW–addition of 0.3% of a conventional yeascell wall extract; YCWs–addition of 0.3% of a yeast cell wall extract with high mannan oligosaccharide solubility. Twenty-four beagledogs were used, eight per food, distributed on a block design. Blocks lasted 32 days, and TNF-a, IL-6, IL-10, ex vivo production ofhydrogen peroxide and nitric oxide by peripheral neutrophils and monocytes, phagocytic index, and fecal IgA were evaluated at thebeginning and end of each period. Additionally, nutrient digestibility, feces production and quality, and fermentation products werequantified. The results were evaluated by analysis of variance and compared using the Tukey test (P<0.05), using the basalimmunological parameters as a covariate. The inclusion of YCWs reduced fat digestibility (P<0.05), increased the concentration ofbutyrate and putrescine, and reduced lactate in feces (P<0.05), showing that mannan oligosaccharide solubilization resulted inhigher fermentation of this compound and altered the metabolism of the gut microbiota. Lower IL-6 on serum was verified for dogsfed the YCWs diet (P<0.05), suggesting a reduction in the inflammatory activity of dogs. Higher phagocytic index was verified forperipheral monocytes after the intake of the YCW food, suggesting better innate immunity. In conclusion, the solubilization of themannooligosaccharide fraction alters its interaction with gut microbiota and biological actions in animals, although both yeast cellwall preparations exhibited prebiotic effects on dogs. |
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