A Coxiella mutualist symbiont is essential to the development of Rhipicephalus microplus

The cattle tick Rhipicephalus microplus is a hematophagous ectoparasite that causes important economic losses in livestock. Different species of ticks harbor a symbiont bacterium of the genus Coxiella. It was showed that a Coxiella endosymbiont from R. microplus (CERM) is a vertically transmitted mu...

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Detalles Bibliográficos
Autores: Guizzo, Melina Garcia, Parizi, Luis Fernando, Nunes, Rodrigo Dutra, Schama, Renata, Albano, Rodolpho Mattos, Tirloni, Lucas, Oldiges, Daiane Patrícia, Vieira, Ricardo Pilz, Oliveira, Wanderson Henrique Cruz, Leite, Milane de Souza, Gonzales, Sergio Alberto, Farber, Marisa Diana, Martins, Orlando, Vaz Junior, Itabajara da Silva, Oliveira, Pedro Lagerblad de
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Brasil
Institución:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Repositório Institucional da UFRGS
Idioma:inglés
OAI Identifier:oai:www.lume.ufrgs.br:10183/173408
Acceso en línea:http://hdl.handle.net/10183/173408
Access Level:acceso abierto
Palabra clave:Parasitologia veterinária
Microbiologia aplicada
Rhipicephalus microplus
Carrapato bovino
Simbiose
Genômica
Bacterias gram-negativas
Descripción
Sumario:The cattle tick Rhipicephalus microplus is a hematophagous ectoparasite that causes important economic losses in livestock. Different species of ticks harbor a symbiont bacterium of the genus Coxiella. It was showed that a Coxiella endosymbiont from R. microplus (CERM) is a vertically transmitted mutualist symbiont, comprising 98% of the 16S rRNA sequences in both eggs and larvae. Sequencing of the bacterial genome revealed genes for biosynthetic pathways for several vitamins and key metabolic cofactors that may provide a nutritional complement to the tick host. The CERM was abundant in ovary and Malpighian tubule of fully engorged female. Tetracycline treatment of either the tick or the vertebrate host reduced levels of bacteria in progeny in 74% for eggs and 90% for larvae without major impact neither on the reproductive fitness of the adult female or on embryo development. However, CERM proved to be essential for the tick to reach the adult life stage, as under antibiotic treatment no tick was able to progress beyond the metanymph stage. Data presented here suggest that interference in the symbiotic CERM-R. microplus relationship may be useful to the development of alternative control methods, highlighting the interdependence between ticks and their endosymbionts.

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