Unveiling the Kinomes of Leishmania infantum and L. braziliensis Empowers the Discovery of New Kinase Targets and Antileishmanial Compounds

CNPq, CAPES, and FAPEG for fellowships and funding this work. E.N.M. appreciate support from NIH (grant 1U01CA207160) and CNPq (grant 400760/2014-2). NF is supported by the Medical Research Council (grantMR/K020420/1). DCM is a recipient of a young investigator award from FAPESP (2014/21129-4). CHA...

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Detalles Bibliográficos
Autores: Borba, Joyce Villa Verde Bastos, Silva, Arthur C., Ramos, Pablo Ivan Pereira, Grazzia, Nathalia, Miguel, Danilo Ciccone, Muratov, Eugene N., Furnham, Nicholas, Andrade, Carolina Horta
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Repositório Institucional da FIOCRUZ (ARCA)
Idioma:inglés
OAI Identifier:oai:arca.fiocruz.br:icict/32426
Acceso en línea:https://arca.fiocruz.br/handle/icict/32426
Access Level:acceso abierto
Palabra clave:Leishmania infantum
Leishmania braziliensis
Kinome
Quinases
Reaproveitamento de drogas
Priorização de metas
Kinases
Drug repurposing
Target prioritization
Descripción
Sumario:CNPq, CAPES, and FAPEG for fellowships and funding this work. E.N.M. appreciate support from NIH (grant 1U01CA207160) and CNPq (grant 400760/2014-2). NF is supported by the Medical Research Council (grantMR/K020420/1). DCM is a recipient of a young investigator award from FAPESP (2014/21129-4). CHA has a research fellow in productivity of CNPq. CHA also thanks the “L'Oréal-UNESCOABC Para Mulheres na Ciência” and “L'Oréal-UNESCO International Rising Talents” for the awards and fellowships received, which partially funded thiswork. Additionally, JVBB and ACSwere supported by fellowships from CAPES.