Efeito do envelhecimento e do estresse crônico sobre a reação do tecido conjuntivo subcutâneo: estudo histológico em ratos

Physiological functions undergo a gradual retardation that begins around 25-30 years and extends to the death. Moreover, this change affects most severely the activities more complex and more intricate responses to tensions or stress. The purpose of this study was to evaluate histologically in aged...

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Detalhes bibliográficos
Autores: Rezende, Maria Cristina Rosifini Alves [UNESP], Kusuda, Ricardo, Marinho, Márcio Von Dreiffus [UNESP], Felipini, Renata Callestini [UNESP], Okamoto, Roberta [UNESP], Okamoto, Tetuo [UNESP], Alves-Rezende, Luís Guilherme Rosifini, Garcia-da-Silva, Tales Candido [UNESP], Alves-Claro, Ana Paula Rosifini
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:portugués
OAI Identifier:oai:repositorio.unesp.br:11449/133211
Acesso em linha:http://apcdaracatuba.com.br/revista/Volume_31_01_Jan_2010/v31n1.htm
http://hdl.handle.net/11449/133211
Access Level:acceso abierto
Palavra-chave:Wound healing
Aged
Hypothalamohypophyseal system
Pituitary-adrenal system
Cicatrização de feridas
Idoso
Sistema hipotálamo-hipofisário
Sistema hipófise-supra-renal
Descrição
Resumo:Physiological functions undergo a gradual retardation that begins around 25-30 years and extends to the death. Moreover, this change affects most severely the activities more complex and more intricate responses to tensions or stress. The purpose of this study was to evaluate histologically in aged rats the effect of chronic stress on the reaction of subcutaneous connective tissue. The purpose of this study was to evaluate histologically in aged rats the effect of chronic stress on the reaction of subcutaneous connective tissue. For this purpose, 60 rats were divided into four groups (GI (control), GII (stressed), GIII (elderly) and GIV (aged / stressed) received dorsal subcutaneous implants of polyethylene tubes containing saline solution. In groups of four animals were sacrificed at 7,14 and 28 days postoperatively. The results allowed to observe more intense inflammatory reaction and tissue organization later in the aged animals subjected to stress.