Comparison between four hours and twenty-four hours endogenous creatinine clearances and exogenous creatinine in healthy dogs

The chronic kidney disease is the main cause of kidney illness in dogs. The evaluation of glomerular filtration rate (GFR) is essential for the diagnosis of this disease, using endogenous or exogenous creatinine clearance tests. Two methods of evaluation can be found in Brazil, the dual twenty minut...

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Detalles Bibliográficos
Autores: Silva, Amanda Chítero, Stante, Flávio Henrique Rodrigues, Brum, Alexandre Martini de, Paulino Junior, Daniel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Institución:Universidade Federal de Itajubá (UNIFEI)
Repositorio:Research, Society and Development
Idioma:portugués
OAI Identifier:oai:ojs.pkp.sfu.ca:article/28899
Acceso en línea:https://rsdjournal.org/index.php/rsd/article/view/28899
Access Level:acceso abierto
Palabra clave:Chronic kidney disease
Function tests
Canine.
Enfermedad renal crónica
Pruebas de función
Canino.
Insuficiência renal crônica
Teste de função renal
Caninos.
Descripción
Sumario:The chronic kidney disease is the main cause of kidney illness in dogs. The evaluation of glomerular filtration rate (GFR) is essential for the diagnosis of this disease, using endogenous or exogenous creatinine clearance tests. Two methods of evaluation can be found in Brazil, the dual twenty minutes, and the twenty-four hours one. Ten healthy (verified with hematological, urinalysis, biochemical and physical evaluation) animals with ages between one and eight years and weight around twelve kilograms from the kennel of veterinary hospital of Universidade de Franca was submitted to three kinds of GFR tests (twenty-four hours endogenous creatinine clearance, clearance of exogenous creatinine and four hour endogenous creatinine clearance). Significant difference was found between the results of the methods, indicating that the four-hour endogenous creatinine clearance has potential to be utilized in the veterinarian routine.