Thyroid Metastases from Hepatocellular Carcinoma after Liver Transplantation

Hepatocellular carcinoma (HCC) patients with metastases to the thyroid are extremely rare. A patient who underwent liver transplantation for HCC recurrence had metastatic thyroid recurrence detected 4 years later. A literature review identified six documented cases, analyzing relevant data on HCC wi...

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Detalles Bibliográficos
Autores: Viana, Danilo Dias Avancini, Magalhães, Angel Evangelista Barroso, Silva, Dayane Laura da, Teixeira, Larissa Peixoto, Dias, Larissa Ponte, Lima, Clebia Azevedo de, Hyppolito, Elodie Bomfim, Costa, Paulo Everton Garcia, Coelho, Gustavo Rêgo, Garcia, José Huygens Parente
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Brasil
Institución:Associação Brasileira de Transplante de Órgãos (ABTO)
Repositorio:Brazilian Journal of Transplantation
Idioma:inglés
portugués
OAI Identifier:oai:ojs3.emnuvens.com.br:article/584
Acceso en línea:https://bjt.emnuvens.com.br/revista/article/view/584
Access Level:acceso abierto
Palabra clave:Carcinoma Hepatocelular
Metástase Neoplástica
Neoplasias da Glândula Tireoide
Hepatocellular Carcinoma
Neoplasm Metastasis
Thyroid Neoplasms
Descripción
Sumario:Hepatocellular carcinoma (HCC) patients with metastases to the thyroid are extremely rare. A patient who underwent liver transplantation for HCC recurrence had metastatic thyroid recurrence detected 4 years later. A literature review identified six documented cases, analyzing relevant data on HCC with thyroid metastasis following liver transplantation. There is a prevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) as etiologies of liver disease (83.3%), with alpha-fetoprotein (AFP) levels elevated in five cases. Additionally, the time between the diagnosis of HCC and thyroid metastasis was within 3 years. The patient remains clinically stable in outpatient follow-up, with an 8-month current survival after total thyroidectomy.