Prevalência da infecção latente por Mycobacterium tuberculosis nos transplantados renais
Objective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results. Methods: This was a cross-sectional study of patients age...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2018 |
| País: | Brasil |
| Institución: | Universidade Federal de Minas Gerais (UFMG) |
| Repositorio: | Repositório Institucional da UFMG |
| Idioma: | portugués |
| OAI Identifier: | oai:repositorio.ufmg.br:1843/71141 |
| Acceso en línea: | https://doi.org/10.1590/S1806-37562017000000367 http://hdl.handle.net/1843/71141 https://orcid.org/0000-0002-3884-9507 https://orcid.org/0000-0002-4340-0659 https://orcid.org/0000-0002-2575-6352 https://orcid.org/0000-0003-3267-4985 https://orcid.org/0000-0002-8978-4512 https://orcid.org/0000-0001-7245-4472 |
| Access Level: | acceso abierto |
| Palabra clave: | Tuberculose Teste tuberculínico Hospedeiro imunocomprometido Infecção latente Mycobacterium tuberculosis Transplantados |
| Sumario: | Objective: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemographic, behavioral, and clinical associations with positive tuberculin skin test (TST) results. Methods: This was a cross-sectional study of patients aged ≥ 18 years who underwent renal transplantation at the Renal Transplant Center of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. We included renal transplant recipients who underwent the TST between January 2011 and July 2013. If the result of the fi rst TST was negative, a second TST was administered. Bivariate and multivariate analyses using logistic regression were used to determine factors associated with positive TST results. Results: The sample included 216 patients. The prevalence of LTBI was 18.5%. In the multivariate analysis, history of contact with a tuberculosis case and preserved graft function (estimated glomerular fi ltration rate ≥ 60 mL/min/1.73 m2) were associated with positive TST results. TST induration increased by 5.8% from the fi rst to the second test, which was considered signifi cant (p = 0.012). Conclusions: The prevalence of LTBI was low in this sample of renal transplant recipients. The TST should be administered if renal graft function is preserved. A second TST should be administered if the fi rst TST is negative. |
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