Nasal mucociliary transportability of male and female smokers

INTRODUCTION: Female smoker's present increased susceptibility to several diseases when compared to the opposite gender. However, there are no studies showing differences in nasal mucociliary transport behavior between male and female smokers. OBJECTIVE: To compare the nasal mucociliary transpo...

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Detalles Bibliográficos
Autores: Uzeloto, Juliana Souza, Ramos, Dionei, C F Freire, Ana Paula, G D Christofaro, Diego, Mara C Ramos, Ercy
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/171067
Acceso en línea:http://dx.doi.org/10.1016/j.bjorl.2017.03.006
http://hdl.handle.net/11449/171067
Access Level:acceso abierto
Palabra clave:Características sexuais
Clearance mucociliar
Distúrbio do tabagismo
Fumo
Mucociliary clearance
Mucociliary transport
Sacarina
Saccharin
Sex characteristics
Smoking
Tobacco use disorder
Transporte mucociliar
Descripción
Sumario:INTRODUCTION: Female smoker's present increased susceptibility to several diseases when compared to the opposite gender. However, there are no studies showing differences in nasal mucociliary transport behavior between male and female smokers. OBJECTIVE: To compare the nasal mucociliary transportability in male and female smokers and non-smokers, taking into consideration age, anthropometric data, smoking load and pulmonary function. METHODS: The analysis included 139 individuals (33 men and 37 women smokers and 32 men and 37 women non-smokers). All participants answered an initial interview to obtain personal data and smoking load. Anthropometric data and carbon monoxide in the exhaled air were assessed. Individuals also performed pulmonary function test and Saccharin Transit Time test. To compare saccharin transit time values between men and women, smokers and non-smokers, stratification of all independent variables was performed (sociodemographic, smoking and respiratory variables) into two categories: below and above the median values. RESULTS: There was no difference between men and women, smokers and non-smokers, regarding nasal mucociliary transportability. Significant differences were only observed between non-smokers. Among those with less forced vital capacity values (<97.37% of predicted), women presented mucociliary transport faster than men. Moreover, it was observed influence of BMI and COex (women smokers), FCV and FEV1 (men non-smokers) and FEF25-75% (women non-smokers) on saccharin transit time values. CONCLUSION: Based on the findings of this study, nasal mucociliary transport in male and female adult smokers, apparently healthy, are similar.