Simple electroanalytical method for determination of guanosine in biological sample

A poly glutamic acid film modified electrode exhibited a catalytic response toguanosine oxidation potential and higher peak current value. Linear concentration curve was obtained in the concentration interval of 1.0 a 10.0 μmol L-1 in 0.04 mol L-1 B-R buffer pH 2.0 with a detection limit of 0.198 μm...

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Detalhes bibliográficos
Autores: dos Santos, Daniela Pereira [UNESP], Brunelli, Tamara Fernanda Totta [UNESP], Bianchi, Alex Rodrigo [UNESP], Zanoni, Maria Valnice Boldrin [UNESP]
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/72144
Acesso em linha:http://www.abechem.com/No.%204-2010/2_4_,2010,202-211.pdf
http://hdl.handle.net/11449/72144
Access Level:acceso abierto
Palavra-chave:Electrooxidation
Guanosine
Modified electrode
Poly glutamic acid
Descrição
Resumo:A poly glutamic acid film modified electrode exhibited a catalytic response toguanosine oxidation potential and higher peak current value. Linear concentration curve was obtained in the concentration interval of 1.0 a 10.0 μmol L-1 in 0.04 mol L-1 B-R buffer pH 2.0 with a detection limit of 0.198 μmol L-1. The electrode was used for the determination of guanosine in the potential of +1.1 V (vs. Ag/AgCl) using differential pulse voltammetry (DPV) at urine sample with good recovery. © 2010 by CEE.