Exercício físico moderado em ratas : repercussão no desenvolvimento da obesidade de suas proles
Obesity is an important worldwide health problem. Physical inactivity associated with over intake of rich-calorie food is the major predictor to several chronic diseases observed late in life. We aimed to evaluate the impact of moderate exercise training program in female on blocking/attenuating ove...
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| Tipo de recurso: | tesis de maestría |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Brasil |
| Institución: | Universidade Estadual de Maringá (UEM) |
| Repositorio: | Repositório Institucional da Universidade Estadual de Maringá (RI-UEM) |
| Idioma: | portugués |
| OAI Identifier: | oai:localhost:1/2214 |
| Acceso en línea: | http://repositorio.uem.br:8080/jspui/handle/1/2214 |
| Access Level: | acceso abierto |
| Palabra clave: | Obesidade Exercício físico moderado - Programação metabólica Ciências da Saúde Educação Física |
| Sumario: | Obesity is an important worldwide health problem. Physical inactivity associated with over intake of rich-calorie food is the major predictor to several chronic diseases observed late in life. We aimed to evaluate the impact of moderate exercise training program in female on blocking/attenuating overfeeding-obesity onset in their offspring male rats. Methods: Female Wistar rats were exposed to moderated exercise training [treadmill; 3x/week during 13 weeks] from 21 to 90 days-old, including pregnancy. On the same time, controls were remaining sedentary. To guarantee offspring overfeeding, pups with three days-old were randomly standard to 3 pups/dams preferentially male (small litters-NR) or 9 pups/dams (normal litters-NN). Offsprings were divided 4 different groups: from both mother groups were divided in exercised and sedentary [normal litter-mother sedentary (NN-MS), small litter mother sedentary (NR-MS), normal litter mother exercised (NR-ME) and small litter-mother exercised (NR-ME)]. Body weight (BW) gain and food intake were evaluated weekly from 21 to 90 days-old. After anesthesia adult rats were killed. Ovarian (OVA), periepididymal (PER), retroperitoneal (RET) and mesenteric (MES); inguinal (ING) fat pads were isolated and weight.Results: Exercised female rats showed an average 9,86%, 7,55% and 11,20% greater BW, from 21 to 90 days-old, during pregnancy and nursing, respectively than to sedentary ones (p < 0,05). Food intake was increased 21,36%,23,87%, during pregnancy and nursing, respectively in exercised mothers compared to sedentary. Exercised mothers presented lower body fat stores than untrained ones (p < 0,05). SL offspring from sedentary or exercised mothers showed greater BW, food intake and body fat stores than NL ones (p < 0,05). Conclusions: Maternal moderate exercise training including pregnancy did not change obesity onset in their offspring submitted to early overfeeding. |
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