CLINICAL, EPIDEMIOLOGICAL AND IMMUNOLOGICAL STUDY TO AMERICAN TEGUMENTARY LEISHMANIASIS IN A DERMATOLOGY REFERENCE CENTER
Introduction: American cutaneous leishmaniasis (ACL) is an infectious disease caused by protozoa of the genus Leishmania. World leishmaniasis is an important endemic disease and public healthproblem in developing countries. Methods: We conducted a retrospective, descriptive and analytical cross-sect...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | Brasil |
| Institución: | Instituto Lauro de Souza Lima (ILSL) |
| Repositorio: | Hansenologia Internationalis (Online) |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.periodicos.saude.sp.gov.br:article/35004 |
| Acceso en línea: | https://periodicos.saude.sp.gov.br/hansenologia/article/view/35004 |
| Access Level: | acceso abierto |
| Palabra clave: | Leishmaniose Epidemiologia Diagnóstico Imunofluorescencia indireta Reação de Montenegro Leishmaniasis Epidemiology Diagnosis Fluorescent Antibody Technique Montenegro skin test |
| Sumario: | Introduction: American cutaneous leishmaniasis (ACL) is an infectious disease caused by protozoa of the genus Leishmania. World leishmaniasis is an important endemic disease and public healthproblem in developing countries. Methods: We conducted a retrospective, descriptive and analytical cross-sectional study of 34 patients diagnosed with ACL. Statistical analysis was performed using the nonparametric Spearman’s test. Results: The gender involved was male (68%) and female (32%); the age range of 1 to 92 years old. The most common clinical manifestations were localized cutaneous form (79.5%) and the ulcers (56%).The face was main affected area (44%) and the minor time from onset of symptoms to consultation was 10 months (68%) of patients. Montenegro skin test (MST) was performed in 29 patients, being positive in (89.6%) and the indirect immunofluorescence (IIF) in only 16 patients, being positive in 13. The age and the duration of the disease were significantly associated with MST. Conclusions: It was not observed the IFI association with the patient’s age and disease duration. The treatment was in most cases, meglumine antimoniate (71%), followed Pentamidine (17%). The results demonstrated that the serological tests constitute an auxiliary tool and the correlations with clinical and histopathologicalfindings are essential. |
|---|